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Routine Care. Principles of care. 1. 2. Insulin therapy. 3. Blood glucose testing. 4. Dietary advice. 5. Use of HbA1c. 6. Quality of care indicators. Programme. Monitoring growth in childhood. 7. Principles of Care. Goals of care include: Eradicate symptoms.
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Routine Care Presentation title
Principles of care 1 2 Insulin therapy 3 Blood glucose testing 4 Dietary advice 5 Use of HbA1c 6 Quality of care indicators Programme Monitoring growth in childhood 7
Principles of Care • Goals of care include: • Eradicate symptoms. • Prevention of acute complications • Hypoglycaemia • Diabetic ketoacidosis • Optimum growth and pubertal development • Ensure good psycho-social adaptation and function • Prevention of long term complications
Components of care Education Insulin Diet Monitoring Support of the child and family INSULIN FOOD
Management - who? Multi-disciplinary team Medical personnel Diabetes educator Dietician Social worker Psychologist
Insulin therapy Presentation title
Insulin Human insulin Produced by recombinant DNA technology Usually U-100 concentration Beware of older U-40 insulins Different types classified by their duration of action
Short acting regular insulin Onset=30-60 minutes Peak=2-4 hours Duration=4-8 hours Given 30 minutes before meal Actrapid, Humulin R
Rapid acting analogues • Onset: 15 minutes • Peak: 30 min-3 hours • Duration: 3-5 hours • Given 15 minutes before food 1320 Insulin profile 1200 1080 NovoRapid®, adolescents aged 13–17 years 960 NovoRapid®, children aged 6–12 years 840 720 HI, adolescents aged 13–17 years 600 HI, children aged 6–12 years 480 Serum insulin (pmol/L) 360 240 120 0 -30 0 30 60 90 120 180 210 240 270 300 330 150 Time (min) NovoRapid, Humalog, Apidra
Intermediate-acting insulin Onset: 2-4 hours Peak: variable Duration: 10-18 hours Not related to meals Usually twice daily Sometimes 3-4 times/day NPH, Insulatard, Monotard, Protaphane, Humulin N
Insulin profiles Slide no 11 Aspart, lispro, glulisine Regular NPH Detemir Plasma Insulin Levels 0 2 4 6 8 10 12 14 16 18 20 22 24 Hours
Mixing insulin • Fixed ratio combination insulin • Combination of short and long acting insulin • Most commonly 30% and 70% combination • E.g. Actraphane, Mixtard 30 • Two peaks of action • Often used in twice daily regimens • Self-mixed combinations • Mixed regular/rapid insulin with NPH in syringes • Create own mix to suit patient
Insulin therapy No perfect insulin preparation Choice of insulin individualised to give as physiological insulin profile as possible Be careful of the concentration of insulin (U-100, U-40) Need proper storage of insulin Compliance with treatment regimen is key to success
Insulin regimens • Twice daily regimen • Mix of short acting and long acting before breakfast and supper • Multiple daily injections • Intermediate or long acting insulin twice daily • Short acting insulin with each meal
Insulin regimens Slide no 15 MDI with Lantus-Levemir CSII
Blood glucose testing Presentation title
Blood glucose testing • Treating diabetes dependent on blood glucose changes during the day • Identify times when at risk for hyper- or hypoglycaemia • Blood levels related to • Insulin regimen and doses • Pattern of eating • Activity / illness • Blood glucose information is used to help patient and family learn – not done for staff!
Interpretation Needs records of insulin, food, activity, etc.
Patterns of testing (1) • Pre- and post-meals, bedtime (7 tests/day) • Pre-meals, bedtime (4 tests/day) • Pre-breakfast, pre- and post-selected meal for 1 week (3 tests/day) • Change selected meal weekly • When symptoms of hypoglycaemia occur • When a top-up dose of insulin is needed for extra food or during illness
Patterns of testing (2) • Strips are expensive • Patterns determined by • Availability of strips • Insulin regimen • Level of control • Patient factors • Pattern changed to get useful information • Needs patient records of food and insulin for readings to be valuable!
Dietary advice Presentation title
Principles Need to have a healthy diet Amount and proportions appropriate for age and growth Carbohydrate content of food matched with insulin regimen Understanding of how to match insulin with food is key Best done with the assistance of a dietician
Dietary review Taken at diagnosis Review regularly (annually) Correct food, correct amount and correct times Review food patterns, activities and insulin regimen Growth and stage of puberty influence diet
Use of HbA1c Presentation title
What is HbA1c Red blood cells contain Haemoglobin (Hb) Glucose sticks onto Hb HbA1c Slow and irreversible HbA1c reflects average blood glucose over 2-3 months High glucose = increased HbA1c Non diabetics: 4-6% (normal range)
What does it tell us Measure of the average blood glucose Correlates with risk of long-term complications Rising HbA1c requires action Ideal HbA1c <6.5% fix slide pix Add EAG table vs A1c???
Quality of care indicators Presentation title
Remember Vital to measure regularly the progress of diabetes Basic patient indicators measured at every visit (e.g. once a month) Measurement of growth a very good indicator of the quality of care Each visit an opportunity for repeated information and education
Monitoring growth in childhood Presentation title
Growth Growth follows a predictable pattern over time Growth can be affected by diabetes, i.e. insufficient insulin dosing can cause stunted growth even if blood glucose levels seem fine Type 2 diabetes, overweight contributes to the diabetes Normal growth indicator of adequate diabetes care
Growth charts Can use population specific charts Center for Disease Control (CDC) charts Charts specific for boys and girls and for different age ranges Height, weight, BMI
Measurements Measure height and weight at each clinic visit, once every three months, at least twice a year Record in medical chart and plot on growth chart Standing height without shoes For young children under 2.5 years, total body length should be measured Measure weight to nearest 0.1 kg if possible
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