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Review Article Acute Pulmonary Embolism. Victor F. Tapson, M.D. N Engl J Med Volume 358(10):1037-1052 March 6, 2008. Summary. Acute pulmonary embolism may occur rapidly and unpredictably and may be difficult to diagnose.
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Review ArticleAcute Pulmonary Embolism Victor F. Tapson, M.D. N Engl J Med Volume 358(10):1037-1052 March 6, 2008
Summary • Acute pulmonary embolism may occur rapidly and unpredictably and may be difficult to diagnose. • Treatment can reduce mortality, and appropriate primary prophylaxis is usually effective. • This review focuses on the pathogenesis, diagnosis, and treatment of acute pulmonary embolism of thrombotic origin.
Outline • Epidemiology and Pathophysiology • Risk Factors • Acquired Risk Factors • Genetic Disorders and Thromboembolic Risk • Diagnostic Approaches • Clinical Manifestations • Preliminary Laboratory Testing and Pretest Probability • Imaging Studies • Treatment • Anticoagulation • Placement of a Vena Caval Filter • Treatment of Massive Pulmonary Embolism • Complications of Thrombolytic Therapy • Prognosis • Prevention • Pregnancy and Acute Pulmonary Embolism • Conclusions
Pathophysiology of Pulmonary Embolism Tapson V. N Engl J Med 2008;358:1037-1052
Risk Factors for Venous Thromboembolism Tapson V. N Engl J Med 2008;358:1037-1052
Clinical Prediction Scores for Suspected Acute Pulmonary Embolism Tapson V. N Engl J Med 2008;358:1037-1052
Contrast-Enhanced CT Angiograms Showing Acute Pulmonary Embolism Tapson V. N Engl J Med 2008;358:1037-1052
Diagnostic Approach to Suspected Acute Pulmonary Embolism Tapson V. N Engl J Med 2008;358:1037-1052
Treatment of Acute Pulmonary Embolism Tapson V. N Engl J Med 2008;358:1037-1052