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Embryology. Introduction & Gametogenesis. INTRODUCTION. Embryology : Study of prenatal stages of development from the fertilization of the ovum to the birth of the new individual. Descriptive Embryology Comparative Embryology Experimental Embryology. Uses.
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Embryology Introduction & Gametogenesis
INTRODUCTION Embryology : Study of prenatal stages of development from the fertilization of the ovum to the birth of the new individual. • Descriptive Embryology • Comparative Embryology • Experimental Embryology
Uses • Helps us understand human anatomy better • Helps us understand why some children are born with organs that are abnormal • May help us prevent or treat such abnormalities
Introduction • First 9 months of every individual spent within the womb • During this period we develop from 1 cell to organism with billions of cells • 2 stages- • Embryo- first 2 months • Fetus- 3rd month to birth
Subdivisions • General embryology • Systemic embryology
Haeckel's Dictum "ontogeny recapitulates phylogeny”
CHROMOSOME NUMBER IN SOMATIC CELLS • MAN WOMAN • 44 XY 44XX • 46 46
Chromosome number • Males 44+ x y females 44+xx • If gametes have the same no. ? • 44xy+ 44xx = 88xxxy ?
GAMETES • OVUM SPERM • 22 X 22X 44XX FEMALE • OVUM SPERM • 22 X 22 Y 44XY MALE
EMBRYO • Male gamete+ female gamete= embryo • Sperm + ovum = zygote (embryo)
Gonads & Gametes • Male gonad- Testis • Male gamete- Spermatozoa
Gonads & Gametes • Female gonad- Ovary • Female gamete- Ovum
Gametogenesis • Process of formation and development of specialized generative cells, called gametes or germ cells. • During this process chromosome number is halved • Diploid haploid • and cell shape is altered
MATURATION OF OVUM Primary Ovarian Follicle Antral Follicle Graffian follicle
COMPARISON • OOGENISIS • Maturation starts as early in the 7th month of IUL • 1st & 2nd meiotic division are not continuous. • Nuclear division is equal but the cytoplasmic division is unequal. • Only one ovum formed • Life span- 24 to 48 hours. • Size of matured Ovum 135 microns. • SPERMATOGENESIS • Maturation starts during puberty, the germ cells are kept dormant. • 1st & 2nd meiotic division are continuous without arrest. • Nuclear division and the cytoplasmic division is equal. • 4 spermatids formed • Life span- 48 to 72 hours. • Length of matured sperm 45 microns.
ABNORMAL GAMETES Abnormal sperms Abnormal oocytes