High-Quality pharmaceutical Desiccant Packaging Solutions For Healthcare Product

1. Pharmaceutical Packaging Pharma Desiccants • Pharma Desiccant is serving worldwide clients by providing high-quality and effective desiccant packaging solutions for protecting healthcare products.

2. What Pharma Is about?

4. What is Primary Pharma Packaging ?

5. Major Problems During Packaging • Protection • Moisture • Oxygen • Mechanical damage • Light

6. Regulatory & Filing terms • USFDA – USA marketing • EU – European Countries –standards • 21 CFR – Code of Federal Regulations • Filing Terms • ANDA - Abbreviated New Drug Application • NDA - New Drug Application

7. Pillow paks • DesiccantslikeSilicagel,MolecularSieves,Carbon,etcoramixtureofsuchpackedinDuPontTyvek. Continuous strip - Roll Form – I mark & Whole Punch DESICCARE -Pillow paks

8. Tyvek Properties • It has outstanding porous microbial barrier & is non leaching and odorless. • Best Strength, Non Tearable Material. • Best Moisture Permeation. • Inertness to most chemicals. • Air permeability • Clean peeling seals • Low fiber tear.

9. Available Desiccants • Silica gel • Molecular Sieves • Activated Carbon • Montmorillonite Clay • Silica gel + Carbon • Silica gel + molecular Sieves

10. Application and Sizes • Meets USFDA and EU standards • Packaging of variety of products like pharmaceuticals, vitamins, Biological, Medical Devices, Food, Optical, Clothing, Electronics and other Consumer Products • Available Sizes- 0.25 Gm, 0.5 Gm, 0.75 Gm, 1 Gm, 1.5 Gm, 2 Gm, 3 Gm, 5 Gm, 10 Gm, 12 Gm and 14 GM • Also available in continuous roll form upto 5 gm.

11. Adsorption Rates at Low Humidity Levels • At lowrelative humidity,Clay adsorbs more moisture than SG as time goes on. • MS adsorbs the most at a quickest rate. MS Clay SG

12. Adsoprtion Rates at High Humidity Levels • At highrelative humidity,SG adsorbs more moisture than Clay as time goes on. • MS adsorbs a lot of moisture quickly at first and then reaches capacity. SG MS Clay

13. Montmorillonite Clay • Montmorillonite clay is a naturally occurring adsorbent created by the controlled drying of magnesium aluminum silicate of the sub-bentonite type. • However, this property causes clay to give up moisture readily back into the container as temperatures rise. • Clay is a good basic desiccant that works satisfactorily below 120°F (approximately 50°C). Above 120° F, there is a possibility that the clay will give up moisture rather than pulling it in, so anticipated storage and transportation conditions should be considered. • Clay is highly effective within normal temperature and relative humidity ranges. Its appearance is that of small gray pellets.

14. UNIT PAKS • Unit Paks are, we can say pillow paks but in larger sizes aremanufactured using DuPont Tyvek® and several custom substrates • 1 unit = 28gms(silica gel, molecular sieve, etc.) according to MIL-D-3464 specifications. • For E.g : Gabapentin Capsules

15. Canister Desiccants • It offers DMF grade desiccants in Canisters. • Canisters (HDPE- High Density Polyethylene ) are small, rigid, cylindrical containers filled with desiccants.

16. Available Desiccants in Canisters • Silica gel • Molecular Sieves • Activated Carbon (OdorControl) –Tyroxine • Silica gel + Carbon • Silica gel + molecular Sieves

17. Application and Sizes • Meets USFDA and EU standards • Used along with moisture sensitive tablets , capsules which are packed in bottles. • Mainly in Pharmaceuticals and Nutraceuticals. • For Eg :Donepezil Tablets, Chlorpromazine HCL Tablet 10 , 25, 50, 100 & 200 Mg • Available Sizes- 1 gm, 2 gm, 3 gm.

19. O-Sorb • “O-Sorb”isdesignedtoremovetheOxygencontentinside • anypackagedenvironment. • O-Sorb’sUniqueblendofabsorbentswillpickup • approximatelythreetimesitsweightof oxygenpreventing • theharmfuleffectsofOxygen. • ProductsComplyto:USFDA,EU,21CFR.

20. Contents

21. Application and Sizes • Protection of API/formulation (Tablets and Capsules, Dry powder) in bottle packing against oxygen for oxygen sensitive molecules • Available Sizes- 10 CC ,20 CC ,30 CC, 50 CC, 100 CC, 200 CC, 500 CC, 1000 CC, 2000 CC,   3000 CC -O-Sorb .

22. PHARMACEUTICAL COILS • Pharma Desiccants is the brand for pharmaceutical coils. • DMF grade type-III material • Coils are available in 3 types: • Cotton • Polyester • Rayon

23. COTTON COIL

24. RAYON COIL

25. POLYESTER COIL

26. Uses & Applications

27. FOAM PLUGS • Foam plugs are white , cylindrical, made of poly-urethane. • Widely used as a filler with tablets, capsules when bottled. • Foam Plugs are tested for their performance with respect to health standards as per ACUTE SYSTEMIC TOXICITY TEST.

28. Features

29. Applications & Size Available • Void space filler • Protection for tablets from chipping due to rattling. • Available in cylindrical shapes

30. Desiccant Tablets • MOC: • Molecular sieve powder,4A • Silica Gel Powder Both used for MVTR testing – Blister,Alu-Alu packing. • MOC: • Calcium Chloride For HDPE bottles testing -MVTR

31. Thank You