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Rapid and uncontrollable development and production of cells.

Cancer. Rapid and uncontrollable development and production of cells. Development of Cancer Cells. Inheritance may increase risk Proto-oncogenes and tumor suppressor genes mutate or become damaged by carcinogens Known carcinogens: Viruses and bacteria Environmental chemicals Tobacco

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Rapid and uncontrollable development and production of cells.

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  1. Cancer Rapid and uncontrollable development and production of cells.

  2. Development of Cancer Cells • Inheritance may increase risk • Proto-oncogenes and tumor suppressor genes mutate or become damaged by carcinogens • Known carcinogens: • Viruses and bacteria • Environmental chemicals • Tobacco • Radiation • Dietary factors

  3. Conversion • Conversion begins with a mutation (a change in DNA) by: • Chemical • Physical • Biological Conversion

  4. Production of Cancer Cells Development and Progression

  5. Development & Progression of Cancer • Begins when a chemical substance stimulates growth of a mutated cell • Those chemical substances influence a 2nd stage of carcinogens called promoters. • Promoters stimulate cell to divide uncontrollably • Metastasis- cancer traveling to other sites; like a forest fire

  6. Development of a Benign Tumor

  7. Development of a Malignant Tumor

  8. Overview of Cancer Development

  9. Ultraviolet Radiation & Skin Cancer ozone

  10. Ozone

  11. Ozone • Screens out 99% of harmful UV light • Ozone produced by lightening • 1% in ozone will result in a 2% in skin cancer • Holes in ozone: • Dupont- CFCs: hairspray, refrigerators, air conditioning • Which country has the highest rate of skin cancer?

  12. CFC’s and Ozone Depletion

  13. Antarctica Sept 2011

  14. Sunburn

  15. Both UVA and UVB are responsible for photoaging and sunburn. Tanning beds produce both UVA and UVB rays

  16. Strong melanoma candidate

  17. Melanoma facts From 1996 to 2000, the national average rate for melanoma was 17.5 for every 100,000 people, while the state of Hawaii average was 15.1 cases per 100,000.

  18. Factors that may also influence the chance of getting melanoma include • Fair skin or freckles. • Being male. • Family or personal history of melanoma. • Chronic UV light exposure. • Severe sunburns. • Unusual moles or a large number of moles. • Weak immune system.

  19. Skin Cancer ABCDE’s of Skin Cancer

  20. Testing • Genetic testing • Biopsy • Blood test • X-rays, PET, MRI • Visual & tactile observation

  21. Treatments • Surgery • Radiation • Chemotherapy • Homeopathy

  22. Prevention • Know family history • Get regular medical screenings • Learn self-exam techniques • Avoid direct sunlight • Watch your diet and weight • Don’t smoke • Drink alcohol in moderation (alcohol decrease heart disease, but increases risk of certain cancers) • Become educated

  23. Lung Cancer

  24. Cervical Cancer • Chromosomes: 82 • four copies of chromosome 12 • three copies of chromosomes 6, 8, and 17 • Cells provided: • Polio vaccine • research into cancer • AIDS • effects of radiation • Effects of toxic substances • gene mapping http://www.cbsnews.com/8301-205_162-57597182/lacks-family-nih-reach-agreement-on-hela-cell-genome-data/

  25. Cervical Cancer Vaccine Controversy Michelle Bachmann Bashes HPV vaccine Gardasil Vaccine http://www.npr.org/blogs/health/2011/09/13/140445104/pediatricians-fact-check-bachmanns-bashing-of-hpv-vaccine

  26. INQUIRY • What do CFC’s do? • What is a proto-oncogene? • Name 3 carcinogens. • What are the ABCD’s of skin cancer? • What is the function of ozone? • Who is Henrietta Lacks?

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