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Toxicology: A History

Toxicology: A History. History of Drugs and the Legislation made to control them. Before we can learn History…. We need to learn drug classifications and categories. Drug categories:. Depressants Stimulants Hallucinogens Date-rape drugs Steroids. Depressants .

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Toxicology: A History

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  1. Toxicology: A History History of Drugs and the Legislation made to control them

  2. Before we can learn History… • We need to learn drug classifications and categories

  3. Drug categories: • Depressants • Stimulants • Hallucinogens • Date-rape drugs • Steroids

  4. Depressants • Depressants slow down your central nervous system to make you sleepy and lethargic

  5. Types of Depressants: • Alcohol- the most commonly abused drug • Alcohol is physically addictive with dangerous withdrawal symptoms

  6. Alcohol Blood Levels • As the blood level rises, the toxic effects become more pronounced • 0.03% = giddy emotions • 0.08% = legal limit- coordination, reaction time, and judgment decline • 0.12% = nausea and vomiting • 0.25% = likely to enter coma • 0.30% = Deep Coma • 0.40% = Death

  7. Types of Depressants • Opiates: chemicals derived from the sap of poppies

  8. Opiates • Opiates: • Are Narcotic Sedatives (sleep producing) • Are Analgesics (pain relieving) • Produce: • Euphoria • Lethargy • Coma and Death (in large doses)

  9. Examples of opiates: • Morphine • Codeine • Heroine • Hydrocodone (vicodine) • Oxycodone (oxycotton) • Methadone

  10. Barbiturates • Derived from barbituric acid and used as sleeping pills and anti-seizure medicine • Most common form: phenobarbital

  11. Stimulants • Stimulants increase alertness, lessen fatigue, and suppress appetite. • With continued use, they cause: irritability, anxiousness, aggressive behavior, paranoia, fatigue, and depression

  12. Stimulant side effects: • Tachyphylaxis- the body gets used to the drug and lessens the effect. In order to get high, the user must take more and more

  13. Type of Stimulants • Amphetamines- increases the levels of hormones in the body • Meth (methamphetamines)

  14. Examples of Stimulants: • Xanthine (Xanax) • Caffeine • Nicotine • Meth • Ephedrine/Pseudoephedrine • Adderall • MDA and MDMA • Cocaine

  15. Hallucinogens • Alter perceptions and mood, lead to delusional thinking, and cause hallucinations

  16. Hallucination v. delusion • Hallucination: sensoryexperience that isn’t real and may affect any or all of the senses • Delusion: false beliefs that have little or no basis in reality

  17. Types of Hallucinogens: • Marijuana • Cacti and Mushrooms • Chemicals

  18. Marijuana • Most commonly used and mildest hallucinogen • Derived from the Cannabis sativaplant • Active Ingredient: Tetrahydrocannibinol(THC)

  19. Cacti and Mushrooms • Peyote- small Mexican cactus used in Native American rituals • Mushrooms- possession isn’t illegal, but use is

  20. Chemicals • Made in a laboratory • Common chemicals: • Lysergic Acid Diethylamide(LSD) • Phencyclidine (PCP)

  21. Date-Rape Drugs • Cause: • Sedation • Compliance • Poor Judgment • Memory Loss

  22. Common Date-Rape Drugs • Rohypnol (flunitrazepam) • Ecstasy • GHB • Ketamine

  23. Steroids • Appear natural in small amounts • Cause muscle growth, increased strength, and improved reflexes when taken in large amounts

  24. Negative effects of Steroids • Hair Loss • Impotence • Liver Damage • Aggressive Behavior

  25. Controlled Substances Act • 1970 act- made manufacture, importation, possession, use and distribution of certain substances regulated

  26. Schedule I controlled substance • High potential for abuse • No accepted medical use • Lack of safety for use of the drug

  27. Examples of Schedule I • GHB • Heroin • LSD • Marijuana • Mescaline

  28. Schedule II controlled substance • High potential for abuse • Has a currently accepted medical use • Abuse of drug may lead to dependence

  29. Examples of Schedule II • Cocaine • Opium • Oxycodone • Morphine • Adderall • Vicodin

  30. Schedule III controlled substance • Has potential for abuse less than other drugs in I and II • Currently accepted as medical treatment • Abuse may lead to moderate or low dependence

  31. Examples of Schedule III • Anabolic Steroids • Ketamine • Codeine when mixed with pain killer

  32. Schedule IV controlled substance • Low potential for abuse • Currently accepted as medical treatment • Lead to limited dependence

  33. Examples of Schedule IV • Phenobarbital • Nuvigil (stimulant)

  34. Schedule V controlled substance • Low potential for abuse (lower than any other schedule) • Currently accepted as medical treatment • Very limited dependence

  35. Examples of Schedule V • Cough suppressants with codeine

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