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Correlating Phase with Iron Deposition in Alzheimer Disease

Muhammad Ayaz M.S. Wayne State University Biomedical Engineering Dept. MRI institute. Correlating Phase with Iron Deposition in Alzheimer Disease. Recently Graduated. Introduction. Role of Iron in Alzheimer disease Purpose of this project

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Correlating Phase with Iron Deposition in Alzheimer Disease

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  1. Muhammad Ayaz M.S. Wayne State University Biomedical Engineering Dept. MRI institute Correlating Phase with Iron Deposition in Alzheimer Disease Recently Graduated

  2. Introduction • Role of Iron in Alzheimer disease • Purpose of this project • Iron deposition in different areas of brain

  3. Conclusion • After studying 75 subjects, we have found that the variation in phase follows a Gaussian statistics with a standard deviation of 30 units. Therefore, if we find a subject whose values fall below 3 standard deviations (90 units) of the mean, then these areas might be considered abnormal or high in iron contents.

  4. Future Directions • Rescanning and data analysis of subjects • Keeping track of any phase variations

  5. Magic of SWI Before SWI After SWI

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