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Biosafety and Biohazardous Materials: An Introduction

Biosafety and Biohazardous Materials: An Introduction. Biosafety at ISU. Biosafety The application of knowledge, techniques and equipment to prevent personal, laboratory and environmental exposure to potentially infectious agents or biohazards. Biosafety Officer

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Biosafety and Biohazardous Materials: An Introduction

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  1. Biosafety and Biohazardous Materials:An Introduction

  2. Biosafety at ISU • Biosafety • The application of knowledge, techniques and equipment to prevent personal, laboratory and environmental exposure to potentially infectious agents or biohazards. • Biosafety Officer • The Biosafety Officer for Iowa State University is Dr. Betsy Matos. To contact Betsy with a question call 294-5359.

  3. Bloodborne Pathogen • Anyone working with human blood or other infectious agents including mammalian cell lines must be enrolled in the bloodborne pathogen program and take bloodborne pathogen training annually. • Details about the program can be found in the Bloodborne Pathogens manual which is on the EH&S website.

  4. Biohazardous Waste Oversight • All biohazardous waste should be decontaminated before disposal. • Be sure to place an “X” over the biohazard symbol on biohazard bags before placing them in the autoclave.

  5. Waste Disposal • All biohazardous waste must be disposed of according to the ISU Sharps and Biohazardous Waste Policy. • Decontamination or disinfection

  6. Sharps Safety • Dispose of sharps in a puncture resistant container. • Do not throw sharps, including plastic pipettes, into the trash.

  7. Biosafety Cabinets (BSCs) • EH&S coordinates the annual certification of biosafety cabinets. • All BSCs used with infectious substances must be certified annually. • EH&S offers training on how to properly use BSCs.

  8. Biosafety Cabinets, Laminar Flow Hoods, and Fume Hoods Clean Bench Biosafety Cabinet Fume Hood

  9. Autoclave Validation • EH&S provides autoclave validation testing (spore vials). • EH&S offers training on how to safely and effectively use autoclaves.

  10. Biological Materials Inventory • A resource for first responders (think firemen) to identify the location of potentially infectious materials in an emergency. • Online database with intuitive data entry tools. Call EH&S 294-5359.

  11. Laboratory Equipment Disposal • Disposed of through ISU Asset Recovery. • All laboratory equipment must be inspected and approved for disposal by EH&S, call 294-5359.

  12. Biohazardous Materials Definition- Materials of biological origin that could potentially cause harm to humans, domestic or wild animals, plants or the environment.

  13. Examples • Transgenic animals or plants • Human, animal or plant pathogens • Biological toxins (such as botulinum toxin) • Human blood and certain human body fluids • Human or non-human primate cell cultures

  14. Bioterrorism—Potential • Bioterrorism use or biological warfare • Bacteria: i.e. Anthrax • Agroterrorism • Plant • Livestock

  15. Regulations Regulations and requirements depend on the type of biological agent used in the research.

  16. USDA

  17. ISU Review Committees • Institutional Review Board (IRB), Human Subjects Committee • Institutional Biosafety Committee (IBC) • Institutional Animal Care and Use Committee (IACUC) • Radiation Safety Committee (RSC)

  18. Biosafety Level Guidelines • CDC and NIH guidelines ensure proper work practices. • ISU Biosafety Manual is a safety resource.

  19. Medical Surveillance • Hazard Inventory • Vaccinations and testing • What to do if exposed. View of inventory form

  20. Points of Contact • Betsy Matos, Anne Dombroski, Amy Helgerson, Steve Ziegenfuss. EH&S 294-5359

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