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MRS Entrepreneurship Challenge: Lab-on-chip Sensor Technology

MRS Entrepreneurship Challenge: Lab-on-chip Sensor Technology. Presented on December 6, 2005. Team Background . Rachel Weaver, BME, MT Ryan Dempsey, BME, MT Charles Bloom, BME, MT John Richardson, BME, Economics Experienced in BioMEMs Peter Shanahan, BME, Mathematics

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MRS Entrepreneurship Challenge: Lab-on-chip Sensor Technology

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  1. MRS Entrepreneurship Challenge: Lab-on-chip Sensor Technology Presented on December 6, 2005

  2. Team Background • Rachel Weaver, BME, MT • Ryan Dempsey, BME, MT • Charles Bloom, BME, MT • John Richardson, BME, Economics • Experienced in BioMEMs • Peter Shanahan, BME, Mathematics • Experienced in BioMEMs

  3. Entrepreneurship Challenge • Scientists and business students will form “virtual teams” to develop a 12-slide PowerPoint presentation • Present startup technology to a panel of venture capitalist judges at 2006 MRS spring meeting • The grand prize is $3,000 • See  http://www.mrs.org/entrepreneur/index.html for more information

  4. BioMEMs Technology • BioMEMs: Biological micro-electromechanical systems • Uses photolithography and soft-lithography • Miniaturized device potential • Single cell reactions • Multiple experiments per chip • In vitro apparatus simulates in vivo cellular environment

  5. Clark Oxygen Sensor • anode & cathode submersed in an electrolytic fluid • Linear relationship between [O2] and current produced

  6. Market potential • Biological applications • Cell cultures • Chemical applications • Chemical reaction cost • Pharmaceutical uses • Drug efficacy

  7. Project Cost • 2” by 2” mask will cost roughly $600 • We will only use a fraction of the mask • Each design iteration will run between $50 and $100 • ~4-6 design iterations depending on time • Includes 35 mm film costs • <$100 on office supplies, paper, etc.

  8. Timeline

  9. IWB Problem Formulation and Brainstorming Chart

  10. References • Fabrication of miniature Clark oxygen sensor integrated with microstructure • Ching-Chou Wu, Tomoyuki Yasukawa, Hitoshi Shiku, Tomokazu Matsue • http://www.bme.vanderbilt.edu/srdesign/2005/group25/272_sdarticle.pdf • A BioMEMS Review: MEMS Technology for Physiologically Integrated Devices • AMY C. RICHARDS GRAYSON, REBECCA S. SHAWGO, AUDREY M. JOHNSON, NOLAN T. FLYNN, YAWEN LI, MICHAEL J. CIMA, AND ROBERT LANGER • http://www.bme.vanderbilt.edu/srdesign/2005/group25/BioMEMS_review.pdf

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