Corticosteroid 11 Beta Dehydrogenase Isozyme 1 - Pipeline Review, H2 2018

1. A A R K S T O R E E N T E R P R I S E C O R T I C O S T E R O I D 1 1 B E T A D E H Y D R O G E N A S E I S O Z Y M E 1 P I P E L I N E R 0 E 1 V 8 I E W , H 2 2 W W W . A A R K S T O R E . C O M

2. O V E R V I E W Corticosteroid 11 Beta Dehydrogenase Isozyme 1 11-beta-hydroxysteroid dehydrogenase type 1 is an NADPH- dependent enzyme highly expressed in key metabolic tissues including liver, adipose tissue, and the central nervous system. In these tissues HSD11B1 reduces cortisone to the active hormone cortisol that activates glucocorticoid receptors. This enzyme plays an important role in obesity and insulin resistance.

3. C O V E R S P R O D U C T S F R O M T H E R A P Y A R E A S Healthcare market research reports Metabolic Disorders, Central Nervous System, Ophthalmology, Cardiovascular, Alzheimers Disease, Dementia Associated With Alzheimers Disease, Obesity, Ocular Hypertension, Open-Angle Glaucoma, Cushings Syndrome, Diabetic Complications, Inflammation, Intracranial Hypertension, Metabolic Syndrome, Muscle Atrophy

4. Report is built using data and information sourced F r o m p r o p r i e t a r y d a t a b a s e s , c o m p a n y / u n i v e r s i t y w e b s i t e s , c l i n i c a l t r i a l r e g i s t r i e s , c o n f e r e n c e s , S E C f i l i n g s , i n v e s t o r p r e s e n t a t i o n s a n d f e a t u r e d p r e s s r e l e a s e s f r o m c o m p a n y / u n i v e r s i t y s i t e s a n d i n d u s t r y - s p e c i f i c t h i r d p a r t y s o u r c e s .

5. Scope Reasons to buy -Snapshot of the global therapeutic landscape - Gain strategically significant competitor for Corticosteroid 11 Beta Dehydrogenase information, analysis, and insights to Isozyme 1. formulate effective R&D strategies -Reviews Corticosteroid 11 Beta - Identify emerging players with potentially Dehydrogenase Isozyme. strong product portfolio -Dehydrogenase targeted therapeutics under - Identify the use of drugs for target development by companies and research identification and drug repurposing institutes. - Identify potential new clients or partners in - Covers pipeline products based on various the target demographic stages of development. - Develop strategic initiatives by - Features descriptive drug profiles for the understanding the focus areas of leading pipeline products. companies

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7. R E L A T E D R E P O R T S Corticosteroid 11 Beta Dehydrogenase Isozyme 1 (11 Beta Hydroxysteroid Dehydrogenase 1 or Short Chain Dehydrogenase/Reductase Family 26C Member 1 or HSD11B1 or EC 1.1.1.146) - Pipeline Review, H2 2018 Corticosteroid 11 Beta Dehydrogenase Isozyme-Pipeline Review, H1 2018 11 Beta-Hydroxysteroid Dehydrogenase Type 1(11ßHSD1) Inhibitor -Pipeline Insight, 2018

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