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ILUVIEN

ILUVIEN. DIABETIC MASCULAR EDEMA Most common cause of visual loss Characterised by accumulation of extracellular fluid in the macular which occurs after the break down of the blood-retinal barrier due to dilated hyper-capillaries and micro-aneurysms

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ILUVIEN

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  1. ILUVIEN • DIABETIC MASCULAR EDEMA • Most common cause of visual loss • Characterised by accumulation of extracellular fluid in the macular which occurs after the break down of the blood-retinal barrier due to dilated hyper-capillaries and micro-aneurysms • Deposition of fluid causes thickening and swelling of the macular and leads to distortion of vision as cones are present in this area • Primary treatment for DME is Laser Photocoagulation and Vitrectomy. • ILUVIEN • Recently approved as a treatment for DME • It weighs 0.18mg and dispenses 0.2µg of the drug daily • It is the only drug therapy for DME treatment • In phase II trials for the treatment of wet and dry AMD and RVO • Active ingredient is fluocinolone acetonide • DELIVERY • injected intra-vitreally using a 25 gauge needle. • minimally invasive procedure, no need for suture • Non-erodible insert • Designed to deliver drug for up to 3 years • Easier to deliver then retisert because of its smaller size

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