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Mitosis is a process of cell division that produces two identical daughter cells from one parent cell. It is essential for the growth and repair of multi-cellular organisms. This article explains the phases of mitosis and its significance in the cell cycle.
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Cell Division Mitosis
Mitosis • Produces 2 cells – called daughter cells – from one parent cell • Daughter cells are identical to each another and to the original parent cell • Most body cells reproduce this way • Similar to binary fission • Asexual reproduction of organisms without a nucleus
Mitosis • Occurs because: • Multi-cellular organisms grow in size and complexity by making more cells • Old and damaged cells are continuously replaced by the division of cells • Single-celled organisms such as bacteria divide to make new, independent organisms • Binary fission – asexual reproduction
Mitosis • The nucleus of the cell divides in two • The nucleus contains the genetic material – chromosomes – of the organism • Chromosomes are made of DNA
MitosisThe Cell Cycle • The nucleus divides in several phases: • Interphase • Prophase • Metaphase • Anaphase • Telophase
MitosisInterphase • Technically not part of mitosis • A resting phase • DNA (Chromosomes) copies itself exactly (replicates) • Organelles double in number, to prepare for division
MitosisProphase • Nuclear membrane disappears • Spindle fibers (or aster fibers) form at the ends of the cell • Chromosomes coil up and become short and fat - become visible • Takes about an hour
MitosisMetaphase • Chromosomes in pairs line up along the equator – middle of cell • Spindle fibers attach to the center of the chromosome pairs • Centromere – the connecting point of the two chromosomes • Takes about 15 minutes
MitosisAnaphase • Chromosomes divide • Chromatids (half of a chromosome pair) separate and are pulled to opposite ends of the cell by the spindle fibers • Takes about 10 minutes
MitosisTelophase • Nuclear membrane forms around each group of chromosomes • Chromosomes unwind and become long and thin again • Cytokinesis begins
MitosisCytokinesis • Cytoplasm divides • One cell becomes two individual cells • Different in plants and animals • Animals: • Cell membrane pinches in • Plants: • Cell wall forms down the center http://www.dundee.ac.uk
Animation http://www.johnkyrk.com/mitosis.html
Animation http://www.cellsalive.com/mitosis.htm