Mastering the Art of Writing a Cancer Biology Scientific Research Proposal- Pubrica.com

1. MASTERING THE ARTOFWRITING A CANCER BIOLOGY RESEARCHPROPOSAL A presentation byDr.NancyAgens, Head, TechnicalOperations info@pubrica.com

2. Outline ofTopics TODAY'SDISCUSSION • Need for a Cancer Research Proposal • Opportunities in Cancer Research • Sample Research Proposal • FiveSecretstoWriteanEffectiveCancerBiologyResearchProposal • Essential Ingredients of the Cancer Research Proposal • CommonPitfalls

3. In the event that you are keen and desirous execute a cancer biology research for your PhD,Itisnecessarythatyoucreateacancerbiologyresearchproposal. TheresearchproposalwouldbetheinitialstepinthedirectionofyourPhD. The research proposal pertaining to your topic would lay down and map everythingthat youaresupposedtoexecuteatthetimewhenyouexecutetheactualresearch. An excellent cancer biology research proposal would necessarily meet the below mentioned generalrequirements. NEED FOR A RESEARCHPROPOSAL

4. CANCER BIOLOGY RESEARCH AREAS

5. How the normal biological programs of cell proliferation and death are altered during cancer & how the immune system responds to tumors. • Researchers are now studying the molecular mechanisms and signaling pathways of cancer cell development, proliferation, and metastasis. • The discovery of tumor stem cells in a range of cancers created opportunity • To identify these rare cells in both solid tumors & hematologic cancers, as well as to investigate the role of these cells at different stages of disease. • The recognition that the cancer cell is in a symbiotic relationship with the tumor microenvironment has created opportunities • to study the interactions of cancer cells within the tumor or the host microenvironment. OPPORTUNITIES IN CANCER BIOLOGY

6. Researchers are also investigating the role of the human microbiome—the community of microorganisms that inhabit the human body—in the initiation and progression of tumors. • New genetic technologies developed over the past decade have helped researchers examine the functional effects of genetic alterations that underlie the development of cancer. These tools have also been used to study epigenetic changes associated with cancer, mechanisms of DNA damage and repair, and gene regulation in cancer cells. • The introduction of increasingly powerful structural biology approaches has allowed researchers • to characterize the structures of mutant proteins involved in cancer, such as RAS, and other molecules in greater detail than had been possible previously. • Through approaches that allow the characterization of the entire proteome, researchers are integrating genomic analysis with the analysis of the proteins in tumor cells to learn, in detail, how cancer-associated mutant proteins affect other proteins. CONTD.

7. FIVE SECRETS TO WRITE AN EFFECTIVE CANCER BIOLOGY RESEARCHPROPOSAL

8. Time is a major factor within the process of writing a researchproposal. Effective management of time could play a vital role when you write a cancer biology researchproposal. Every aspect needs to be planned and allocated a timeframe. You have to factor in time taking procedures overwhich you have nocontrol. Acquiring feedback or discussing some aspect of your research with your guide, can betime-consuming. COMMENCINGEARLY:

9. Check your university library or online electronic databases to find samples of cancer biology PhDthesis. • You can only consult such papers to acquire an understanding of how it isdone. • At no time should you resort to plagiarizing contents from the samplethesis. READING SAMPLEPAPERS:

10. Title of the Project SAMPLEFORMAT Short title Why you should investigate ? Research Problem or need for the study

11. Aim of the study SAMPLERESEARCH OBJECTIVES Objectives

12. Literature review is important when you are writing the researchproposal. • When you are writing the cancer biology research proposal, make sure that you accord due importance to the literaturereview. You should use PubMed, a website (http://www.ncbi.nlm.nih.gov/pubmed/) that provides free access to biomedical journal citations and abstracts mainly indexed by Medline. FINDLITERATURE: Literature to Support Your Statement

13. SPECIFY METHODS: How you wanted to conduct your study. Methods specifications Methods specifications

14. SPECIFY ORIGINALITY Outcome of the study

15. At the time when you commence writing your proposal, you have to first inventorize yourresources. • Resources would include; the libraries that you would be having access to, access to research facilities for facilitating the research • It would be wise here to stray away from cancer biology topics for which you lackresources. GIVE THOUGHTTO AVAILABLE RESOURCES

16. 5 ASSISTANCE: SEEKINGPROFESSIONAL • It is not at all easy to write a cancer biology research proposal,so it is better to seek professional assistance as and when the needarises. • You can certainly avail assistance from your professors, but if you are confused about the whole process, you can always seek professional assistance.

17. ESSENTIAL INGREDIENTS OF THEPROPOSAL YouractualPhDresearchoncancerbiologylargelyreliesontheprovision of a research proposal that clearly convinces a panel of experts with regardstothesignificanceoftheresearchtothedomain. Theproposalwouldalsoclearlyprojectthatyouareinapositiontojustify theresearchandexecuteitasperthenecessarystandards. Youshouldmakesurethatyoucoverthebelowmentionedpointswithin your proposal on cancerbiology. Youshouldensurethatyourresearchproposalincancerbiologyiscreated meticulously if you intend to get your proposal approved and proceed further with your PhDthesis. Contd..

18. Exemplifytheproblemthatyouareattemptingresolvethroughyourresearch andemphasizeitssignificanceinyourdomainwithinyourintroduction. Provideanextensivereviewofexistingliteraturetoindicatethatyouhavea thorough command on the research that has already been executed in yourdomain. Clearlyindicateyourchoiceofresearchmethodologyandalsojustifywhy youhavechosenthesaidmethodologyasthiswillprovideaclearpicture to thereader. Presentaclear,realistictimelineandtheresourcesthatyouwouldrequire to complete theresearch. Offeracrystalclearhypothesisorresearchquestiontoyourreader. ESSENTIAL INGREDIENTS OF THEPROPOSAL

19. COMMONPITFALLS Methodology: Sequence ofWork: Originality: Atthetimeofselecting the topic, it isimperative to deliberate about the research methodology with yourguide. Plan your proposal, create an outlineand then commence the writingwork. Conduct extensive literature review in your domain to understandthe current gaps in cancer biology. Choose a unique and previously not researchedtopic.

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