Expected

Sep 18, 2014

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Parp-2 +/+. Parp-2 +/+. Parp-2 +/+. Parp-2 +/-. Parp-2 +/-. Parp-2 +/-. Parp-2 -/-. Parp-2 -/-. Parp-2 -/-. a. p53 -/- pups (From Parp-2 +/- p53 +/- intercrosses). Expected. Observed. Pups born in relation to expectation (%). *. b. p53 -/- pups

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Expected

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Parp-2+/+ Parp-2+/+ Parp-2+/+ Parp-2+/- Parp-2+/- Parp-2+/- Parp-2-/- Parp-2-/- Parp-2-/- a p53-/- pups (From Parp-2+/-p53+/- intercrosses) Expected Observed Pups born in relation to expectation (%) * b p53-/- pups (From Parp-2+/-p53-/- x Parp-2+/-p53+/-) Expected Observed Pups born in relation to expectation (%) * c E13.5 p53-/- embryos (From Parp-2+/-p53-/- x Parp-2+/-p53+/-) Expected Observed Embryos (%) Nicolas et al. Fig. S1