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Glioblastoma And the size of the tumors effect on the motor cortex

Glioblastoma And the size of the tumors effect on the motor cortex. By: Renae Howington Tripken AP Psych. WHY?!.

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Glioblastoma And the size of the tumors effect on the motor cortex

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  1. GlioblastomaAnd the size of the tumors effect on the motor cortex By: Renae Howington Tripken AP Psych

  2. WHY?!...... • THIS MAN RIGHT HERE!!!!...I decided to do this project because of my papaw. He was diagnosed about 5 months ago with Giloblastoma Cancer. He means the world to me and I just wanted to find out more information on his cancer.

  3. Things you NEED to know… • asymptomatic condition: cancer hasn’t come to a notice. There are no symptoms. • hemi paresis: is weakness on one side of the body.

  4. What is Glioblastoma??! • Glioblastoma is a type of cancer that starts in the brain or spine. It is called a glioma because it arises from glial cells. The most common site of gliomas is the brain. • Glioblastoma is known to be the WORST form of brain cancer there is! It is like a spider web, the cancer itself spreads up through the lesions in the brain and spreads across.

  5. My Hypothesis… • I believed that the larger the tumor the worse that the ability to use the motor cortex would decrease significantly. Not only would it effect the ability to use your limbs (arms, legs) but also the use of your face and other functions such as using the restroom, and chewing.

  6. Major Findings • Glioblastoma effects the motor cortex based on placement and size of the tumors. • Glioblastoma is not a direct symptom cancer. *** In other words it doesn’t pop right out to anyone*** • The cancer may take 1 to 2 years to fully form and cause harm.

  7. Major Findings continued…. • The symptoms of cancerinclude seizure, nausea and vomiting, headache, and hemi paresis, • the single most prevalent symptom is a progressive memory, personality, or neurological deficit due to temporal and frontal lobe involvement. • The kind of symptoms produced depends highly on the location of the tumor, more so than on its pathological properties. The tumor can start producing symptoms quickly, but occasionally is an asymptomatic condition until it reaches an enormous size

  8. Causes • GBM is more common in males, although the reason for this is not clear. It may be due to the fact that males eat more and thus increase their chances of eating something that is virus-infected. Most glioblastoma tumors appear to be sporadic, without any genetic predisposition. A viral link remains the strongest causal agent. No links have been found between glioblastoma and smoking, diet, or electromagnetic fields, however the evidence regarding a link with cellular phone use remains equivocal. • Some also believe that there may be a link between polyvinyl chloride (which is commonly used in construction) and glioblastoma. A recent link cited in the Lancet medical journal links brain cancer to lead exposure in the work place.

  9. Other risk factors…. • Sex: male (slightly more common in men than women) • Age: over 50 years old • Ethnicity: Caucasians, Asians • Having a low-grade astrocytoma (brain tumor), which often, given enough time, develops into a higher-grade tumor • Having one of the following genetic disorders is associated with an increased incidence of gliomas: Neurofibromatosis, Tuberous sclerosis, Von Hippel-Lindau disease, Li-Fraumeni syndrome, Turcot syndrome

  10. Effects • Effects from Glioblastoma include…loss of feeling in face, arms and legs. Slurred speech, tiredness, loss of use of face, arms, legs, and urinary tract. • These could also include diagnosis of Hypoglycemia or Diabetes.

  11. Prime Example

  12. Cure/Medication • The only way to help to cure or stop the cancer is through radiology and chemotherapy. Medication is prescribed to help the nauseating, and blood sugar levels.

  13. Interview on Dowell Richardson • Dowell Richardson: Age:64 Health: Minor Heart problems Diagnosis: March 2011 Relation: Grandfather

  14. Interview continued…. • Q.: What were some of your minor symptoms that you had before you found out you had cancer. • A : Minor coughs, chest pains, and headaches, numbness and tingling in my left side. I completely found out that I had Glioblastoma Cancer when I was sent to the hospital in March for symptoms of a stroke. • Q : What most effected you after the cancer began to grow? • A : The use of my legs and the left side of my face began to lose feeling and usage of the left side of my face.

  15. Continued…. • Q : Now that your radiology and chemotherapy has started how do you feel? • A : I am very sleepy all the time, I haven’t became nauseated yet, that may be due to the medicine.

  16. Conclusion • In my conclusion my hypothesis was correct. The larger the tumor, the worse off the motor cortex can be effected. • The loss of limbs and facial use can also be effected by the tumor size.

  17. References • Dowell Richardson- Interview. • www.ncbi.nim.nih.gov/m/pumbed/11003273/ • http://www.braintumor.org/patients-family-friends/find-support/support-networl/patient/patient-support-network.html?tumor_type=gliolastoma-multiforme-&age_range • http://radiology.rsna.org/content/248/3/971.full.pdf • Clark, A. (2009) Brain Tumors. Lucent Books, 27500 Drake Rd. Farmington Hills, MI 48331. Thompson and Gale.

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