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Supplementary Immunization Activities Quality, Risks and Risk Management. IEAG Meeting 13 July 2011. Supplementary Immunization Activities (SIAs) India, Jan to June 2011. Endemic & risk states. Endemic & risk states. Zone 1 UP/Bihar, Delhi & HR areas. Jan. Feb. Mar. Apr. May. Jun.
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Supplementary Immunization ActivitiesQuality, Risks and Risk Management IEAG Meeting 13 July 2011
Supplementary Immunization Activities (SIAs) India, Jan to June 2011 Endemic & risk states Endemic & risk states Zone 1 UP/Bihar, Delhi & HR areas Jan Feb Mar Apr May Jun NID SNID mop up in West Bengal / Jharkhand
SIAs – India, January to February 2011 23 Jan 27 Feb 2nd week Feb mOPV1 mOPV3 bOPV tOPV
bOPV tOPV SIAs – India, March to June 2011 March April May June
Key Immediate Actions that followed detection of case Mop up conducted Vaccine & other logistics reach blocks • National level partners meeting • Media plan operationalized • Vaccine arrived in district • State & District Task Force Meetings • 14 additional SMOs arrive in districts • IEC plan developed • Marker pens & other logistics procured • Field Investigation (NCDC/NPSP/UNICEF) • National Technical Group Meeting • Decision on mop up Chief Minister & Chief Secretary WB informed by GoI Wild Polio virus notified Day 0 Day5 Day 1 Day 2 Day 3 Day 4 Day 6 7 Feb 2011 13 Feb 2011
Major Issues Identified • Microplanning • Missed Areas • High work load of vaccinators & supervisors • Composition of vaccination teams not appropriate • No revisits planned to ‘X’ houses • Training • Weak interpersonal communication skills of vaccinators • Untrained vaccinators working as team members • Non-acceptance of vaccine • High refusals (~ 47000 refusals in Howrah and 3 neighbouring districts) • Myths against vaccine safety
Outbreak Response Actions(GoI/ GoWB, WHO-NPSP, UNICEF, Rotary, CORE) • Identification of 36 high risk blocks/municipalities & 222 high risk Gram Panchayats/wards to focus activities • Enhanced oversight & coordination by central and state officials, DMs, CMOs, Municipality/ Ward Officers, BDOs, BMOs
Outbreak Response Actions (2)(GoI/ GoWB, WHO-NPSP, UNICEF, Rotary, CORE) • 25 experienced additional SMOs deployed to the outbreak area for 4 months to support • Improvements in microplans: ensure no missed areas, appropriate team composition and workload • Trainings: to improve skills & performance of vaccinators and supervisors • Intensive monitoring of preparedness & implementation in high risk areas
Outbreak Response Actions (3)(GoI/ GoWB, WHO-NPSP, UNICEF, Rotary, CORE) • Scale up of IEC/ mobilization efforts • 1900 NGO mobilizers deployed • Additional IEC materials produced • Enhanced media support • Sensitization of Influencers/ religious leaders and local practitioners • Advocacy/ vaccination during community events • Health Camps • Vaccination at clinics of important practitioners • Mandatory revisits to ‘X’ marked houses accompanied by doctors/ local influencers
Outbreak response, West Bengal WPV1 notified 07 Feb 2011 7 weeks 1 week 5 weeks 17 weeks WPV1 notified 12 Feb 2010 Howrah, 2011 7 6 WPV1 5 WPV3 Number of WPV 4 3 2 1 1 2 3 4 5 6 7 Murshidabad, 2010 bOPV mOPV1
Summary – SIAs in 2011 • At least one SIA with tOPV conducted in all areas in the country – most areas got 2 tOPV rounds • 3 to 5 campaigns conducted with bOPV in high risk areas • Aggressive Emergency Outbreak Response conducted in West Bengal following detection of WPV type 1 in Howrah district in 2011
Areas/ Populations at highest risk of polio Areas with recent polio transmission
Areas/ Populations at highest risk of polio Areas with recent polio transmission Endemic areas
Endemic areas Areas/ Populations at highest risk of polio Areas with recent polio transmission Areas with high migrant populations
Areas with recent transmission West Bengal JharkhandMalegaon (Maharashtra)
Northern districts, West Bengal Percent unvaccinated children End-of-round survey Percent N= 1,371 4,490 2,996 4,020 3,515 6,556 7,574 7,686 7,065 10,320 Southern districts, West Bengal Percent 7,525 6,665 8,193 11,933 11,027 11,787 N=
Quality of SIAs in southern districts - West Bengal Percent unvaccinated children, End-of-round survey, 2011 Howrah Kolkata Percent Percent N= 1,451 2,220 2,674 3,995 3,629 3,393 1,423 N= 2,158 762 1,034 1,487 2,092 24-Parganas North 24-Parganas South Percent Percent N= 1,153 866 2,067 2,535 2,858 2,846 2,018 N= 2,405 2,347 1,998 2,341 2,847
Pakur & Sahibganj Percent 2,945 3,213 5,904 9,779 8,398 6,088 4,163 5,568 5,509 6,197 6,151 N= High coverage achieved in high risk areas of Jharkhand Percent unvaccinated children, End-of-round survey Jharkhand West Bengal
Jharkhand West Bengal Lot Quality Assurance Sampling (LQAS) West Bengal & Jharkhand – Feb to June 2011 Hypothesis:“The SIA coverage in this LOT is > 90%.” Only 1 of 46 lots rejected in North Bengal/Jharkhand during last 5 SIAs LQAS findings validate monitoring findings from end-of-round surveys
Malegaon Municipal Corporation Percent unvaccinated children, End-of-round survey Percent 1,989 4,424 4,193 3,151 3,844 3,946 3,115 3,155 3,798 N= # houses with reluctance to accept OPV, End-of-round Number
Summary – Areas with recent transmission • West Bengal (Northern districts): Improvement in SIA quality since September 2010 - sustained over last 9 months – a few pockets of low coverage persist • West Bengal (Southern districts): Rapid improvement in SIA quality during past 4 months, however quality variable in districts; pockets with gaps in quality remain – require immediate addressal • Jharkhand: Sustained good quality campaigns over last 9 months • Malegaon (Maharashtra): Large proportion of unvaccinated children during multiple rounds – recent worsening of quality
Endemic Areas Western UPCentral Bihar
Continued intensive focus on vaccination in field huts - Kosi area, Bihar • > 280,000 clusters of field huts (basas) visited by vaccination teams each round • Intensive supervision and monitoring Percent unvaccinated children detected in field huts (basas) ~ 3,000 children checked per round
High polio vaccination coverage sustained in 107 highest risk blocks of UP and Bihar West UP 2009 2010 2011 Bihar 2009 2010 2011 Percent unvaccinated children – end of round survey 66 HR blocks ~40,000 children checked for vaccination status each round in 107 high risk blocks 41 HR blocks
Lot Quality Assurance Sampling (LQAS), 66 highest risk blocks, West UP, June 2011 – A Pilot Hypothesis:“The SIA coverage in this LOT is > 95%.” HR blocks in which LQAS done
Zinc distribution to children with diarrhea 107 highest risk blocks of UP and Bihar Percent households having a child with diarrhea that had received Zinc tablets, June 2011 1% 22% Households checked =2,115 Household checked =1,444 Source: NPSP SIA monitoring data
Summary – Endemic Areas • Intensive series of SIAs conducted with bOPV in endemic areas in first half of 2011 • High coverage during polio SIAs being sustained in the high risk areas of UP and Bihar • Implementation of certain components of 107 high risk block plan remain a challenge
Areas with high migrants / mobile populations Migrant populations vaccinated 5-6 times (Jan to June 2011) # children: 0.8 mn in each round # children: 0.7 mn in each round # children: 0.5 mn in each round # children: 1.1 mn in each round Delhi, Mumbai, Punjab, Haryana, Gujarat, Uttarakhand, West Bengal
Percent unvaccinated children, End-of-round survey Delhi Gr. Mumbai Percent Percent 2,608 1,201 2,681 2,802 4,432 6,189 8,490 9,366 9,715 11,430 2,218 2,640 2,631 2,611 3,214 6,028 5,297 5,320 5,503 N= N= Punjab Gujarat Percent Percent 3,054 3,725 6,163 8,421 5,943 5,988 6,084 537 650 5,454 6,306 534 804 804 N= N=
Continuous vaccination along Indo-Nepal border NEPAL Uttar Pradesh INDIA Bihar Vaccination post Blocks with vaccination post 81 vaccination posts ~314,000 children vaccinated (April to June 2011)
Coverage during major religious congregations/ population movement • Ajmer Urs (Rajasthan) • 22 May to 14 June 2011 ~ 300,000 children vaccinated 2. Piran Kaliyar (Uttarkhand):Feb 2011:~60,000 children vaccinated 3. Holi - returnee migrants (West Bengal, UP, Bihar): March 2011: ~245,000 children vaccinated 4. Planned activity: Shrawani Mela (Bihar & Jharkhand): July – August 2011: ~300,000 children expected to be vaccinated
= 10 migrant sites Migrants sites identification, India – June 2011 Number of sites identified by type Number of sites with migrants identified : 150,000 Number of children < 5 yrs in these sites : ~ 4.2 million
Summary – Coverage of migrants • Intensive SIAs to vaccinate migrants in high risk states during first half of 2011 • Quality of coverage of migrants variable in different states • Additional opportunities to vaccinate migrants at congregations, borders being utilized • National data base of migrant families being prepared
Conclusions • Number and scope of SIAs during first half of 2011 conducted as recommended by last IEAG • Aggressive outbreak response conducted in West Bengal in early 2011 • Endemic areas sustaining high SIA coverage • Strategy to cover migrants in high risk states and other areas being optimized • Overall SIA quality in areas with recent transmission improved in 2011, however certain pockets remain a matter of concern
Questions for consideration of IEAG • What is the optimum number, timing and scope of SIAs between July and December 2011? • What should be the scope and number of SIAs during early 2012? • What types of polio vaccines should be used in the SIAs?
Proposed SIAs – India, July to December 2011 (As recommended by Nov 2010 IEAG) SNID SNID Jul Aug Sep Oct Nov Dec Sep Nov bOPV
Monthly incidence of WPV1 cases, 2005-2011 25 Planned SNID Most recent SNID conducted 20 Planned SNID 15 10 5 0 Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec