Understanding the role of nitrogen generators in chromatography

1. Understanding the role of Nitrogen Generators in Chromatography Nitrogen generators are widely used in various sectors related to chromatography. Nitrogen generators are used in chromatography where a stable and continuous requirement of nitrogen supply is necessary. LC-MS nitrogen generators and nitrogen generators as gas chromatographs are widely applied in chromatography.

2. LC-MS is an acronym for Liquid Chromatography-Mass Spectrometry. It is an analytical chemistry technique used widely to determine the various different constituents of complex mixtures of certain chemicals and other effluents.  The technique is generally used and found in analytically advanced science laboratories. For the proper functioning of the LC-MS system there is an acute need for LC-MS nitrogen generators. The nitrogen supply can be static, in other terms stored particularly in big cylinders and tanks or can be dynamically generated on the laboratory itself. Importance of purity of nitrogen used for LC-MS The purity of nitrogen is the thing that needs the most concern. About 95% of the purity in the nitrogen gas is recommended. The remaining 5% is the oxygen gas which has not been found during the time of analysis through generators. Manufacturing companies need to take the concern of using only high-quality materials while manufacturing. The nitrogen generators used as gas chromatography and LC-MS equipment are generally manufactured by materials which are Phthalate and Butylatedhydroxytoluene (BHT).

3. Phthalate and BHT can have a powerfully negative effect on the quality of Oxygen gas which composes about 5% of total air. How do nitrogen generators help in lab workflows? Having a nitrogen generator as a gas chromatograph in laboratories provides significant ease in the overall functioning of the laboratory. There is no need for the workers to monitor and check the gas cylinder’s level again and again. It also eliminates any unwanted disruption between the analyses. The gas can be generated on the demand of the laboratory. LC-MS nitrogen generators ensure the availability of gas in the lab all the time, eliminating any supply issues and delays of nitrogen gas cylinders.  Replacing nitrogen gas cylinders with LC-MS nitrogen gas cylinders is economically feasible for the laboratory. A typical LC-MS requires about 10,000 Liters of nitrogen per day. It is an alarming quantity. It consumes about one cylinder every day for laboratory use. LC-MS nitrogen generators are much feasible economically for laboratory use.

4. Nitrogen generators are much safer Nitrogen generators are much safer gas chromatographs. Nitrogen gas can create an asphyxiating environment. To avoid such accidents there is a particular need to use supplements that eliminate the chances of leakage in the site. Source https://quadrexcorp.home.blog/2020/05/18/understanding-the-role-of-nitrogen-generators-in-chromatography/