1 / 1

Fig. 1

Fig. 1. IL-1R1 WT. IL-1R1 KO. Trap Vehicle. 35 mg/kg mIL-1 Trap. B. A. 5. 5. 4. 4. Neutrophils (X10 6 )/mouse. Neutrophils (X10 6 )/mouse. 3. 3. 2. 2.

quana
Download Presentation

Fig. 1

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Fig. 1 IL-1R1 WT IL-1R1 KO Trap Vehicle 35 mg/kg mIL-1 Trap B A 5 5 4 4 Neutrophils (X106)/mouse Neutrophils (X106)/mouse 3 3 2 2 Supplementary Figure 1. Blocking IL-1 reduced neutrophil influx in crystal-induced peritonitis and air pouch models. (A) IL-1R1 KOs showed fewer CPPD-induced peritoneal neutrophils (PBS: n=4 WT; n=3 IL-1R1 KO / CPPD: n=8 per genotype). (B) mIL-1 Trap (35 mg/kg) reduced CPPD crystal-induced peritoneal neutrophils (PBS: n=4 Vehicle / CPPD: n=6 per group). + p< 0.01; # p < 0.001 compared to controls. Data expressed as means + SEM. WT: IL-1R1 WT mice; KO: IL-1R1 knockout mice. 1 # + 1 0 0 CPPD PBS PBS CPPD

More Related