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135526. www.hop.man.ac.uk/painresearch. www.medicine.manchester.ac.uk. MODULATION OF LASER EVOKED POTENTIAL FREQUENCY RESPONSE TO PAIN LOCALISATION, AFFECT AND DISTRACTION El-Deredy, Wael 2 , 1 ; Boyle, Yvonne 1 ; Bentley, Deborah E. 1 ; Jones, Anthony K. 1 .

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  1. 135526 www.hop.man.ac.uk/painresearch www.medicine.manchester.ac.uk MODULATION OF LASER EVOKED POTENTIAL FREQUENCY RESPONSE TO PAIN LOCALISATION, AFFECT AND DISTRACTION El-Deredy, Wael2, 1; Boyle, Yvonne1; Bentley, Deborah E.1; Jones, Anthony K.1. 1. Human Pain Research Group, Division of Neuroscience and Medicine-Hope, University of Manchester, Salford, UK. 2. The School of Psychological Sciences, University of Manchester, UK 70 60 50 40 30 70 60 50 40 30 Frequency Frequency 0 100 200 300 400 500 Time (ms) 0 100 200 300 400 500 Time (ms) 70 60 50 40 30 70 60 50 40 30 70 60 50 40 30 70 60 50 40 30 70 60 50 40 30 70 60 50 40 30 0 100 200 300 400 500 Time (ms) 0 100 200 300 400 500 Time (ms) 0 100 200 300 400 500 Time (ms) 0 100 200 300 400 500 Time (ms) 0 100 200 300 400 500 Time (ms) 0 100 200 300 400 500 Time (ms) Localisation with noise (LW) Localisation no noise (LN) F 70 60 50 40 30 70 60 50 40 30 C R L Frequency Frequency 0 100 200 300 400 500 Time (ms) 0 100 200 300 400 500 Time (ms) 70 60 50 40 30 70 60 50 40 30 70 60 50 40 30 70 60 50 40 30 70 60 50 40 30 70 60 50 40 30 0 100 200 300 400 500 Time (ms) 0 100 200 300 400 500 Time (ms) 0 100 200 300 400 500 Time (ms) 0 100 200 300 400 500 Time (ms) 0 100 200 300 400 500 Time (ms) 0 100 200 300 400 500 Time (ms) Unpleasantness no noise (UN) Unpleasantness with noise (UW) a. Unpleasantness without noise Unpleasantness without noise Localisation without noise Localisation with noise 280-305ms 118-136ms 185-215ms c. b. 118-136ms 185-215ms 280-305ms 280-305ms 118-136ms 185-215ms

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