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MRC myeloma IX : effet de la maintenancesur la SSP en fonction du statut MRD post-autogreffe

MRC myeloma IX : effet de la maintenancesur la SSP en fonction du statut MRD post-autogreffe. La maintenance par thalidomide améliore significativement la SSP en cas de MRD positive (p = 0,036), ce qui n’est pas le cas pour les MRD négative (p = 0,11). Patients MRD positive.

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MRC myeloma IX : effet de la maintenancesur la SSP en fonction du statut MRD post-autogreffe

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  1. MRC myeloma IX : effet de la maintenancesur la SSP en fonction du statut MRD post-autogreffe • La maintenance par thalidomide améliore significativement la SSP en cas de MRD positive (p = 0,036), ce qui n’est pas le cas pour les MRD négative (p = 0,11) Patients MRD positive Patients MRD négative Log-rankp = 0,1103 HR = 0,76 ; IC95 : 0,54-1,07 Log-rankp = 0,0360 HR = 0,64 ; IC95 : 0,42-0,97 Thal ; MRD+ (n = 93) NM ; MRD+ (n = 93) Thal ; MRD+ (n = 53) NM ; MRD+ (n = 53) Patients à risque 53 40 30 22 13 7 2 0 53 28 18 12 8 5 4 0 Patients à risque 93 78 60 48 29 20 10 1 0 93 73 50 34 25 15 8 1 0 IMW 2013 – D’après Child JA et al., abstract S7-2, actualisé

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