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Antimicrobial Resistance and You. Donna Riddle, BSMT (ASCP) Epidemiologist Executive Director, Nevadans for Antibiotic Awareness Clark County Health District (702) 383-1378. The Genesis of Resistance Nevadans for Antibiotic Awareness (NAA) Action Items for You At Work At Home
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Antimicrobial Resistance and You Donna Riddle, BSMT (ASCP) Epidemiologist Executive Director, Nevadans for Antibiotic Awareness Clark County Health District(702) 383-1378
The Genesis of Resistance • Nevadans for Antibiotic Awareness (NAA) • Action Items for You • At Work • At Home • In Your Community
The Gram Stain • Gram Positive • Gram Negative
1928: A Mold Changes Medicine • Dr. Fleming’s discovery • Penicillin inhibits bacterial enzymes necessary for cell wall production • Mass production proves difficult
1944 • Military takes penicillin to the battlefield 1945 • Scientists Isolate Resistance
The Next 50 Years • 1950’s By prescription only • 1960 Methicillin introduced • 1961 Methicillin resistance • 2001 62 % of S. aureus resistant • 2000 Linezolid introduced • 2001 Linezolid resistance
How is Sensitivity or Resistance Determined? Disc diffusion: Zones of no growth around antibiotic
Factors of Resistance • Prevalence of resistance genes • Extent of Antibiotic use
Staphylococcus aureus • If S. aureus is resistant to methicillin, it is commonly resistant to cephalosporins and imipenem • Antibiotic of choice: vancomycin • VISA also known as GISA
Antibiotic Resistant Infections Cause: • Prolonged hospital stays • Fewer therapeutic options • Greater costs
Nevadans for Antibiotic Awareness (NAA) • NAA is a statewide task force of over 30 state and local public and private agencies and companies committed to reducing the spread of antibiotic resistance.
NAA Subcommittees • Infection Control • Public Awareness • Provider Education • Surveillance Forming a new subcommittee: Veterinary and Agriculture
Abbott Laboratories, Inc. Albertsons Bristol-Myers Squibb Carson-Tahoe Hospital Clark County Health District CR BARD Medical, Inc. GlaxoSmithKline Pharmaceuticals Health Plan of Nevada, Inc. Insurcorp Integrated Healthcare Services Magnus Translations Nevada State Board of Pharmacy Nevada State Health Division Orgill/Singer Insurance & Investments PacifiCare, Inc. Pfizer Inc. Pharmacia RITE AID Corporation Roche Laboratories Saint Mary’s Health Network Sav-on Sierra Community Healthcare Foundation Sierra Health Services, Inc. Southwest Medical Associates, Inc. Sunrise Hospital & Medical Center The Valley Health System and Owen Healthcare Virgen Advertising Walgreens Washoe Health System Wyeth-Ayerst
NAA Accomplishments • Distributed healthcare guidelines • Begun provider education • Distributed materials to childcare centers • Developed a statewide public education campaign Efforts/ contributions by members are voluntary.
Action Items for Work • Provide home care sheet to patients with antibiotic resistant bacteria • Always note antibiotic resistance on transfer forms
Action Items for Home • Complete full course of antibiotics • Don’t demand antibiotics for viral infections • Wash your hands
Action Items for the Community • Educate family and friends • Support H.R. 1771: Antibiotic Resistance Prevention Act • Buy antibiotic-free meat
The Genesis of Resistance • Nevadans for Antibiotic • Awareness (NAA) • Action Items for You • At Work • At Home • In Your Community • Questions?