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75 trials and 11 systematic reviews a day. Bastian H. 2010 . PLoS Med 7(9):e1000326. PCFDP November 2010. Chris Hooper-Lane, MA, AHIP Ebling Library University of Wisconsin-Madison. Objectives. October 2010 Introduce Ebling Library (access/resources/services)
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75 trials and 11 systematic reviews a day Bastian H. 2010. PLoS Med 7(9):e1000326 PCFDPNovember 2010 Chris Hooper-Lane, MA, AHIP Ebling Library University of Wisconsin-Madison
Objectives October 2010 Introduce Ebling Library (access/resources/services) Introduce and discuss sources of evidence November 2010 (at Memorial Library Computer Lab) Hands-on searching EBM review and single study resources: Cochrane, ACP Journal Club, DARE, PubMed, and more Keeping up to date (MyNCBI, Evidence Updates) January 2011 Putting it all together -- Therapy February 2011 Putting it all together -- Diagnosis
Access to library resources Your Net ID and password Problems: call the DoIT Help Desk at 608-264-4357
Developing clinical questions Background questions • general knowledge of disease • treatment options • secondary/tertiary literature (i.e. texts, reviews) • What? How?
Sources for background questions • Online texts/databases • UpToDate • MDConsult • STAT!Ref • BMJ Clinical Evidence • MICROMEDEX
Developing clinical questions Foreground questions • specific knowledge of managing pts. • primary literature (original studies) • four or three essential components
Clinical Guidelines Meta Analyses EBM / Review literature Systematic Reviews strength of evidence Experimental studies Controlled Trials(randomized RCT) search sequence Cohort (prospective) studies Observational studies Case control (retrospective cohort) studies Cross-sectional studies Case studies / Case Series 9
Meta Analyses EBM / Review literature Systematic Reviews strength of evidence Experimental studies Controlled Trials(randomized RCT) search sequence Cohort (prospective) studies Observational studies Case control (retrospective cohort) studies Cross-sectional studies Case studies / Case Series 11
Cochrane Database of Systematic Reviews Meta Analyses DARE TRIP Database PubMed Systematic Reviews strength of evidence Controlled Trials(randomized RCT) search sequence Cohort (prospective) studies Case control (retrospective cohort) studies Cross-sectional studies Case studies / Case Series 12
Cochrane Database of Systematic Reviews Meta Analyses DARE TRIP Database PubMed Systematic Reviews strength of evidence Controlled Trials(randomized RCT) search sequence ACP Journal Club Evidence Updates (BMJ) Cohort (prospective) studies Case control (retrospective cohort) studies Cross-sectional studies Case studies / Case Series 13
Cochrane Database of Systematic Reviews Meta Analyses DARE TRIP Database PubMed Systematic Reviews strength of evidence Controlled Trials(randomized RCT) search sequence ACP Journal Club Evidence Updates (BMJ) Cohort (prospective) studies PubMed Cochrane CENTRAL Registry Case control (retrospective cohort) studies Cross-sectional studies Case studies / Case Series 14