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به نام خدا

به نام خدا. معرفی داروهای جدید و قدیم در زنان. M.D. O.B. & Gyn. Shahin Golshah . Estrone. Estrodiol. Estriol. Estrogen. Progestrone Process. Progestrone Process. Drospirenone. Contraceptive Patch. Hormones embedded in adhesive layer of the patch Composition: EE/norelgestromin.

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به نام خدا

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  1. به نام خدا

  2. معرفی داروهای جدید و قدیم در زنان M.D. O.B. & Gyn. Shahin Golshah

  3. Estrone Estrodiol Estriol

  4. Estrogen

  5. Progestrone Process

  6. Progestrone Process

  7. Drospirenone

  8. Contraceptive Patch • Hormones embedded in adhesive layer of the patch • Composition: EE/norelgestromin • Applied: abdomen, buttocks, arm • Use 3wks plus 1 patch free wk • Efficacy: 5 preg/5,240 cycles • Mech, indications & side effects:similar to OCPs • Not effective women >180 lbs • Launched: June 2002 OB/GYN News, 2002

  9. Norelgestromin

  10. Cyproterone Compound(Anti Androgenic Progestin)

  11. Combination Oral Contraceptive Pills • Treatment Regimen • 21 hormone days • 7 hormone free days

  12. Oral Contraceptives Available in the US

  13. Oral Contraceptives Available in the US

  14. Diphereline 3.75mg S.R. • 1. NAME OF THE MEDICINAL PRODUCT • Diphereline 3,75mg S.R. powder and solvent for suspension for injection, sustained release form. • INN: triptorelin • 2. QUALITATIVE AND QUANTITATIVE COMPOSITION. PHARMACEUTICAL FORM. • Powder (triptorelin, D,L lactide-coglycolide polymer, mannitol, Carmellose sodium, Polysorbate ) and • solvent (water, mannitol) for suspension for injection (i.m.), sustained release form.

  15. 3. CLINICAL PARTICULARS • 3.1. Therapeutic indications • Prostate cancer. • Treatment of the prostate cancer with metastases. Patients who have not previously received hormone • therapy respond better to Diphereline. • Precocious puberty ( before 8 years in girls and 10 years in boys ). • Genital and extra genital endometriosis (stage I to IV ) • Female infertility • Supplementary treatment in combination with gonadotrophin to induce ovulation with a view to in vitro • fertilisation and embryo transfer (I.V.F.E.T.). • Myoma

  16. - from the outset , one i.m. injection of Diphereline 3.75 mg S.R., repeated every 28 days. • Precocious puberty: • Children weighing more than 20 kg • Endometriosis • The treatment must be started in the first five days of menstrual cycle.

  17. One i.m. injection of Diphereline 3.75 mg S.R. on the second day of the cycle. Gonadotropins should be started after the pituitary desensitisation ( plasma estrogens less than 50 pg/ml ), generally 15 days after injection of Diphereline. 3.3. Contraindications : • Should never be used during pregnancy.

  18. Female infertility • Warnings and precautions: the follicular retrieval may increase markedly in some predisposed patients and particularly in those with polycystic ovarian disease. • 4. PHARMACOLOGICAL PROPERTIES Triptorelin is a synthetic decapeptide analogue of natural GnRH

  19. با تشکر از توجه شما

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