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Detection of Ziram by LC/APCI/MS Hiroshi MORIWAKI Osaka City Institute of Public Health &

Detection of Ziram by LC/APCI/MS Hiroshi MORIWAKI Osaka City Institute of Public Health & Environmental Sciences. Ziram. use. pesticide antifouling agent. toxicity. endocrine disruptor mutagen carcinogen. ((CH 3 ) 2 NCS.S) 2 Zn M.W. 305.8 m.p. 240 Log Pow 1.09. Analysis of Ziram.

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Detection of Ziram by LC/APCI/MS Hiroshi MORIWAKI Osaka City Institute of Public Health &

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  1. Detection of Ziram by LC/APCI/MS Hiroshi MORIWAKI Osaka City Institute of Public Health & Environmental Sciences

  2. Ziram use pesticide antifouling agent toxicity endocrine disruptor mutagen carcinogen ((CH3)2NCS.S)2Zn M.W. 305.8 m.p. 240 Log Pow 1.09

  3. Analysis of Ziram Direct detection by GC/MS　→　× Conventional method Decomposition of the ligand to CS2 × Chemical speciation of dithiocarbamate pesticides LC/MS ( Direct detection of ziram )

  4. Ion mode Ionization Positive ion mode Negative ion mode ESI/MS × × APCI/MS × Corona current<0.6mA × ○ Corona current>0.6mA

  5. Mass spectrum B) A)

  6. Corona current vs. peak intensity

  7. Cone voltage vs. peak intensity

  8. Conditions of APCI/MS

  9. Column separation

  10. Mass chromatogram

  11. Calibration curve

  12. Summary ・ Direct detection of Ziram by LC/APCI/MS ・ Corona current > 0.6mA ・ LC separation: GPC column ・ Instrumental detection limit: 2mg/L Next step ・ Development of the pretreatment ・ Use of LC/MS/MS ref. H. Moriwaki, Y. Yamaguchi and M. Fukushima: Rapid Commun. Mass Spectro., in press (2001).

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