210 likes | 416 Views
PCRRT & ECLS. Dr. Peter Skippen, PICU. BC Children’s Hospital, Vancouver. CANADA. Outline. Indications Options Setups Conclusions. Clinical Scenarios. Acute respiratory failure / acute cardiac failure + acute inflammatory response to ECLS circuit
E N D
PCRRT & ECLS Dr. Peter Skippen, PICU. BC Children’s Hospital, Vancouver. CANADA.
Outline • Indications • Options • Setups • Conclusions
Clinical Scenarios • Acute respiratory failure / acute cardiac failure + acute inflammatory response to ECLS circuit + ongoing uncontrolled septic / inflammatory process + single / multi-organ failure + volume overload / ongoing fluid resuscitation + supporting nutrition
Indications • volume overload • electrolyte / acid - base disorders • mediator clearance • hemofiltration post CPB / cardiac surgery • “making room” • preparing to wean from ECLS
lasix infusion SCUF CVVH CVVHD “home made” customized machine access ECLS circuit separate site Options
ECLS circuits • Biomedicus • VA • VV • Roller pump • VA • VV
Basic ECLS Circuitry Venous line Arterial line H PUMP OXYGENATOR
Biomedicus System - diagram Venous line Arterial line - + <+ H PUMP OXYGENATOR
Roller Pump System - diagram - Venous line Arterial line Venous reservoir (gravity fed) + <+ H + PUMP OXYGENATOR
CRRT & Rollerpump Filter
Options for PCRRT • customized systems eg. PRISMA • home made systems • standard infusion pumps pressure limited • roller pumps NOT pressure limited
Home Made Systems & ECLS: Problems • Infusion Pumps (max. 999mls/hr = 16.66mls/min) • no safety features eg. micro-air detector • may be unable to get adequate blood flow / dialysis flow / filtration flows • Roller Pump Systems (litres/min) • high pressure circuitry no pressure limits • circuit rupture no pressure limits • MUST incorporate bubble trap insert pre-oxygenator
PRISMA & ECLS • Problems • high pressure return pre-oxygenator / high pressure alarm of PRISMA • complexity of circuit? • V-A shunt (depending on placement)
Technique • PRISMA: setup standard • infusion pumps: limited by blood flow rate - SCUF • roller pump circuit: allows flexibility at increased risk • high blood flow • anticoagulation • ECLS circuit already heparinized
Conclusions • specific issues to be considered • biomedicus vs rollerpump • custom device vs. homemade • allows optimized nutritional support • allows weaning from ECLS • may reduce inflammatory response