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This study investigates the impact of different treatment sequences on cholesterol synthesis and plasma lipid levels after 7 weeks of treatment. The study also examines individual changes in cholesterol absorption between treatments.
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Sudhop T. et al. J Lipid Res 2009 Apr 20 [Epub ahead of print]
Treatment Sequences Sudhop T. et al. J Lipid Res 2009 Apr 20 [Epub ahead of print]
Determination of cholesterol synthesis from steady state mass balance after 7 weeks of treatment Sudhop T. et al. J Lipid Res 2009 Apr 20 [Epub ahead of print]
Plasma cholesterol, triglycerides and cholesterol precursor at baseline and after 7 weeks of treatment Sudhop T. et al. J Lipid Res 2009 Apr 20 [Epub ahead of print]
Study flow chart Sudhop T. et al. J Lipid Res 2009 Apr 20 [Epub ahead of print]
Individual changes in fractional cholesterol absorption between placebo and ezetimibe (A) and between simvastatin and ezetimibe/simvastatin (B) treatment Sudhop T. et al. J Lipid Res 2009 Apr 20 [Epub ahead of print]