Plant Hormone Signaling and the Ubiquitin-proteasome System

Nov 11, 2012

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Plant Hormone Signaling and the Ubiquitin-proteasome System

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Proteasome

Proteasome. WHAT WOULD YOU SEE IF YOU RAN THE THE WHOLE PROTEIN EXTRACT FROM A CELL?. WHAT INFORMATION DOES THIS GIVE YOU?. MUTATIONS

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Protein Degradation and Regulation Ubiquitin/Proteasome Pathway Guo Peng, Luo Tong and Yang Kong 2002.12.16

Protein Degradation and Regulation Ubiquitin/Proteasome Pathway Guo Peng, Luo Tong and Yang Kong 2002.12.16. I. Introduction. This pathway is the major non-lysosomal process responsible for the breakdown of most short and long-lived proteins in mammalian cells.

957 views • 48 slides

Ubiquitin

Ubiquitin. By Mr. Szerminski Sample 4U CCT. General info: - it is a regulatory protein that has been found in almost all tissues of eukaryotes - one of its functions: it directs protein recycling - can attach to proteins and label them for destruction.

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Intracellular Protein Degradation- The lysosome and Ubiquitin Proteasome System

Intracellular Protein Degradation- The lysosome and Ubiquitin Proteasome System . Scott Wilson Department Neurobiology 5-5573 Wilson@nrc.uab.edu. Outline. Sites of proteolysis Gastrointestinal tract Circulatory system Intracellular proteolysis Lysosome Biogenesis and function

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Signaling in the innate immune system PRR signaling

Manifestation of Novel Social Challenges of the European Union in the Teaching Material of Medical Biotechnology Master’s P rogrammes at the University of Pécs and at the University of Debrecen Identification number : TÁMOP-4.1.2-08/1/A-2009-0011.

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The role of the ubiquitin-proteasome pathway in rhTRIM5α-mediated restriction of HIV-1

The role of the ubiquitin-proteasome pathway in rhTRIM5α-mediated restriction of HIV-1. Cindy Danielson Thomas Hope Laboratory, Northwestern University. rhTRIM5 α restricts HIV-1. rhTRIM5α prevents infection of rhesus macaques by HIV-1. Sawyer 2005. Towers 2005. rhTRIM5 α restricts HIV-1.

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Signaling System 7

Signaling System 7. In the Old Days. PST – Per trunk Signaling This method was used to set up calls between telephone company exchanges. Still used in some parts of the world but use is declining, according to the text – pg 88, PBX’s use this to communicate with the CO

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Proteasome/Ubiquitination

Proteasome/Ubiquitination. SIGMA-ALDRICH. Proteasome/Ubiquitination

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Lactacystin: An Inhibitor in the Ubiquitin Proteasome Pathway

Lactacystin: An Inhibitor in the Ubiquitin Proteasome Pathway. Ami Jun-Yee Chin February 17, 2005. Chemistry Nobel Prize 2004. Awarded to Aaron Cichanover, Avram Hershko, and Irwin Rose. . Central Dogma of Molecular Biology. DNA. TRANSCRIPTION of RNA. TRANSLATION to Protein.

955 views • 77 slides

Signaling System 7

Signaling System 7. Signaling System 7 PSTN and TDM SS7 State of the Technology 3. Future Trends in Signaling and Networks. Objectives. Define the role signaling plays in a network Compare the different types of applications which use SS7

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Ubiquitin-Proteasome Pathway

Ubiquitin-Proteasome Pathway. SIGMA-ALDRICH. Ubiquitin-Proteasome Pathway

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Plant hormone signaling I

Plant hormone signaling I What is a plant hormone? How to determine if a molecule functions as a hormone or not? Several criteria:

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Hormone Transport and Long Range Signaling

Hormone Transport and Long Range Signaling. The developmental processes that are controlled by auxin flux. Genetics of Auxin Transport. AUX1 proteins : components of auxin influx PIN proteins : components of auxin efflux machinery

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Ca 2+ signaling in plant

Ca 2+ signaling in plant. Light Cold stress Heat shock Mechanical stresses (Touch, wind & Wounding) Pathogen invading Phytohormones (Auxin, ABA, GA) Gravity. Primary Ca 2+ -Signal Decoder. Diverse Cellular Responses. [Ca 2+ ] cyt. Calmodulins CDPKs Other CBPs. AM, FM, DU.

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Signaling System 7

Signaling System 7. Chapter 4. SS7. Used to perform out of band signaling on the PSTN SS7 handles call establishment, exchange of info, routing, operations, billing Used by VoIP Provides link of VoIP to old voice infrastructure. SS7.

555 views • 20 slides

Broad activation of the ubiquitin–proteasome system by Parkin is critical for mitophagy

Broad activation of the ubiquitin–proteasome system by Parkin is critical for mitophagy. Nickie C. Chan , Anna M. Salazar , Anh H. Pham , Michael J. Sweredoski , Natalie J. Kolawa1 , Robert L.J. Graham , Sonja Hess, and David C. Chan

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Lactacystin: An Inhibitor in the Ubiquitin Proteasome Pathway

Lactacystin: An Inhibitor in the Ubiquitin Proteasome Pathway. Ami Jun-Yee Chin February 17, 2005. Chemistry Nobel Prize 2004. Awarded to Aaron Cichanover, Avram Hershko, and Irwin Rose. Central Dogma of Molecular Biology. DNA. TRANSCRIPTION of RNA. TRANSLATION to Protein.

1.02k views • 77 slides

The Ubiquitin Proteosome Pathway

The Ubiquitin Proteosome Pathway. Swati Pradhan Mayura Dange Vidyadhar Daithankar. Overview. Background Protein misfolding & degradation Ubiquitin & proteosome structure Ubiquitin Proteosome Pathway Mechanism Structures of enzymes involved in pathway

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Figure 3 Signaling pathways of growth hormone

Figure 3 Signaling pathways of growth hormone. Brooks, A. J. & Waters, M. J. (2010) The growth hormone receptor: mechanism of activation and clinical implications Nat. Rev. Endocrinol. doi:10.1038/nrendo.2010.123.

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Ubiquitin-Proteasome Pathway

The ubiquitin-proteasome pathway (UPP) is one of the major destruction ways to control the activities of different proteins. The function of UPP is to eliminate dysfunctional/misfolded proteins via the proteasome, and these speciï¬c functions enable the UPP to regulate protein quality in cells. Therefore defects in UPP are expected to disturb cellular homeostasis and are detrimental to cell survival.

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Ubiquitin

Ubiquitination is a key regulatory mechanism attaching the small protein modifier ubiquitin to protein substrates, thereby modifying their structure, cellular location, function, or targeting them for destruction via proteolysis. The process of protein ubiquitylation regulates many aspects of cell function and provides a wealth of drug target opportunities to many therapeutic areas including cancers, cardiovascular, metabolism, inflammation, diabetes, neurodegeneration and infectious diseases. https://www.creative-biogene.com/Services/Drug-Discovery-Services/Ubiquitin-Screening-Profiling-Services.html

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