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P11: Comparison of indirect calorimetry with Quark RMR and M-COVX calorimetres in critically ill patients. 30th November 2013 3rd iFAD– Poster Session 3 Valérie Vanbiervliet Van Biervliet V, Van Regenmortel N, De laet I, Schoonheydt K, Dits H, Malbrain MLNG
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P11: Comparison of indirect calorimetry with Quark RMR and M-COVX calorimetres in critically ill patients 30th November 2013 3rd iFAD– Poster Session 3 Valérie Vanbiervliet Van Biervliet V, Van Regenmortel N, De laet I, Schoonheydt K, Dits H, Malbrain MLNG ICU, ZNA Stuivenberg, Antwerp, Belgium
Indirect Calorimetry • Measurement of Resting Energy Expenditure (REE) • Non-invasivebedsidemethod • Breath-to-breathanalysisthrough gassampling • Spontaneous and mechanically-ventilatedpatients • Gold standard = DeltatracMetabolic Monitor • New methods? • Quarck(Cosmed, Rome, Italy) • M-COVX (DatexOhmeda, Helsinki, Finland)
Study Protocol Patients and Methods: • Retrospective analysis of data on 11 measurements obtained in 8 mechanically ventilated patients. • Exclusion criteria: • FiO2 > 0,6 • Thoraxdrain, or ventilatory leakage • Renal replacement therapy Aims: Comparison of accuracy in the calculation of daily caloric needs and REE with two devices, the M-COVX and the Quark RMR.
Results cont. • Pearson Correlation P<0,01 • M-COVX = 0,46 x Quark + 1092 kCal • Coëfficient of Variation = 14,2%
Results cont. • Bland and Altman Analysis • Mean Bias = 243±239 kCal • Lower Limit of Agreement = -236 kCal • Upper Limit of Agreement = 722 kCal • 28,3% Percentage Error
Indirect calorimetrywith M-COVX has a significant correlationwith the Quark RMR, howeverwith the measurementwith the M-COVX shows a systematicoverestimation of 243 kCal of the REE dailycaloricneeds in comparisonwith the Quark RMR. conclusions