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Peptide Synthesizer C10-GGWWKK and C14-KKGGII

Introducing new instruments for peptide synthesis, including C10-GGWWKK and C14-KKGGII, with mass spectrum of C14-GGIIKK. Supported by ThalesNano H-Cube Mini Plus™ microwave reactor.

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Peptide Synthesizer C10-GGWWKK and C14-KKGGII

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  1. ISIS Deuteration FacilityKun Ma, Peixun Li, Marek Jura and John Webster05/03/2018

  2. New Instruments Peptide Synthesizer C10-GGWWKK C14-KKGGII C10-WWKKGG C14-K C14-GGIIKK C6-AAAK C14-KK Mass spectrum of C14-GGIIKK

  3. ThalesNano H-Cube Mini Plus™

  4. Microwave reactor 200 ℃, D% ~ 40% after 6 hours 180 ℃, D% 84% after 1 hour

  5. Proposals Deuteration requests covering: • FAP 1: Diffraction • FAP 2: Liquids • FAP 3: Large Scale Structures • FAP 4: Excitations • FAP 5: Molecular Spectroscopy

  6. Supported chemicals

  7. Enabling Science Producing Science Faraday Discussions (2017) Soft Matter, (2017) JCIS, 2018,516, 456-465 JCIS, 2018, 512, 231-238 Langmuir, 2017, 33 (38), 9944–9953

  8. Surface multilayer formation

  9. Surface multilayer formation

  10. Lipid-surfactant interaction influenced by hydrophobic chain fluidity

  11. Lipid-surfactant interaction influenced by hydrophobic chain fluidity

  12. Selected Publications • Xu, H.; Thomas, R. K.; Penfold, J.; Li, P. X.; Ma, K.; Welbourne, R. J. L.; Roberts, D. W.; Petkov, J. T., The impact of electrolyte on the adsorption of the anionic surfactant methyl ester sulfonate at the air- solution interface: Surface multilayer formation, Journal of Colloid and Interface Science, 2018, 512, 231-238 • Xu H, Li P., Ma K., Welbourn R.J.L., Doutch J., Penfold J., Thomas, R.K, Roberts D.W., Petkov J.T., Choo K.L., Khoo S.Y., Adsorption and self-assembly in methyl ester sulfonate surfactants, their eutectic mixtures and the role of electrolyte, Journal of Colloid and Interface Science, 2018, 516, 456-465 • Arron Briddick, Rebecca Fong, Elise Sabattie, Peixun Li, Maximilian W. A. Skoda, Florence Courchay, and Richard L. Thompson, Blooming of Smectic Surfactant/Plasticizer Layers on Spin-Cast Poly(vinyl alcohol) Films, Langmuir, 2018, 34 (4), pp 1410–1418 • Christopher P. Cabry, Lucía D'Andrea, Karina Shimizu, Isabelle Grillo, Peixun Li, Sarah Rogers, Duncan W. Bruce, José N. Canongia Lopes, and John M. Slattery, Exploring the bulk-phase structure of ionic liquid mixtures using small-angle neutron scattering, Faraday Discuss., 2018, 206, 265-289 • Zhidi Chen , Jeffrey Penfold , Peixun Li, James Doutchc, Yaxun Fan and Yilin Wang , Effects of length and hydrophilicity/hydrophobicity of diamines on self-assembly of diamine/SDS gemini-like surfactants, Soft Matter, 2017, 13, 8980-8989 • Hui Xu, Peixun Li, Kun Ma, Rebecca J. L. Welbourn, Jeffrey Penfold, David W. Roberts, Robert K. Thomas, and Jordan T. Petkov, Adsorption of Methyl Ester Sulfonate at the Air–Water Interface: Can Limitations in the Application of the Gibbs Equation be Overcome by Computer Purification? Langmuir, 2017, 33 (38), pp 9944–9953 • Charles Smith, Zongyi Li, Robert Holman, Fang Pan, Richard A. Campbell, Mario Campana, Peixun Li, John R P Webster, Steven Bishop, Rojaramani Narwal, Shahid Uddin, Christopher F. van der Walle & Jian R. Lu, Antibody adsorption on the surface of water studied by neutron reflection, mAbs, 2017 , 9(3), 466-475 • A. Chiesa, T. Guidi, S. Carrette, S. Ansbro, G. A. Timco, I. Vitorica-Yrezabal, E. Garlatti, G. Amoretti, R. E. P. Winpenny and P Santini, Magnetic Exchange Interactions in the Molecular Nanomagnet Mn12, Physical Review Letters, 2017, 119 (21), 217202-6. • Griffin, Lucy R.; Browning, Kathryn L.; Clarke, Stuart M.; Smith, Alexander M.; Perkin, Susan; Skoda, M. W. A.; Norman, Sarah E., Direct measurements of ionic liquid layering at a single mica- liquid interface and in nano- films between two mica- liquid interfaces, Phys Chem Chem Phys, 2017, 19 (1), 297-304.

  13. Thanks for your attention!

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