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Quiescent Cells:. frizzled. E-cadherin. -catenin. P. slimb. -catenin. GSK3 . -catenin. conductin/axin. APC. LEF/ TCF. Target Genes. wnt. Activated Cells:. frizzled. dsh. E-cadherin. -catenin. P. slimb. -catenin. GSK3 . -catenin. conductin/axin. APC. LEF/ TCF.
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Quiescent Cells: frizzled E-cadherin -catenin P slimb -catenin GSK3 -catenin conductin/axin APC LEF/ TCF Target Genes
wnt Activated Cells: frizzled dsh E-cadherin -catenin P slimb -catenin GSK3 -catenin conductin/axin APC LEF/ TCF Target Genes
Loss of APC: frizzled E-cadherin -catenin P slimb -catenin GSK3 -catenin conductin/axin APC LEF/ TCF Target Genes