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Journal of Nuclear Medicine 1999; 40:1301-1309 Reporter Hung-Jen Hsieh

Impact of Attenuation Correction by Simultaneous Emission/Transmission Tomography on Visual Assessment of 201 Tl Myocardial Perfusion Images. Journal of Nuclear Medicine 1999; 40:1301-1309 Reporter Hung-Jen Hsieh. Introduction.

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Journal of Nuclear Medicine 1999; 40:1301-1309 Reporter Hung-Jen Hsieh

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  1. Impact of Attenuation Correction by Simultaneous Emission/Transmission Tomography on Visual Assessment of 201Tl Myocardial Perfusion Images Journal of Nuclear Medicine 1999; 40:1301-1309 Reporter Hung-Jen Hsieh

  2. Introduction • It has been shown that for subjects with a low likelihood of CAD, attenuation correction(AC) improves the specificity of defect detection in the inferior wall. • The aim of this study was to investigate the effect of AC on the visual interpretation of the RCA and LAD regions in CAD patients.

  3. Material And Methods • Patients Selection • Cardiological Evaluation: Significant stenosis was defined as>70% luminal diameter reduction, with normal wall motion on ventricular angiography. ECG Q-wave and elevation of CPK enzymes, together with evidence of an akinetic segment supplied by a major epicardial vessel with thrombosis, was necessary to diagnose MI.

  4. Stress/Reinjection Perfusion Imaging • Acqusition Protocol • Visual Analysis: Five point rating scale • Statistical Analysis: The significance of the differences between ROC curves was tested by comparing the areas under the ROC curves(AUCs).

  5. Results And Discussion

  6. Conclusion • AC significantly affects the visual interpretation of 201Tl stress/4 h-delayed SPECT images. • This study confirmed the increase in specificity obtained with AC in the RCA territory. However, in the population considered, the studied AC was deleterious for the LAD territory assessment.

  7. Thanks for your attention!

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