NCI CQIE – Centers of Quantitative Imaging Excellence Program

1. NCI Centers of Quantitative Imaging Excellence Program Jim Gimpel RT (R)(MR) Imaging Analyst ACR Clinical Research Center NCI CQIE – Centers of Quantitative Imaging Excellence Program

2. NCI – CQIE Program NCI CQIE – Centers of Quantitative Imaging Excellence Program

3. NCI – CQIE Program Training and qualification in advanced, quantitative imaging for CT, MRI and PET Centers of Quantitative Imaging Excellence Program (CQIE) To be conducted at 50+ NCI Cancer Centers nationwide On-site and on-line training components Annual renewal program NCI CQIE – Centers of Quantitative Imaging Excellence Program

4. NCI – CQIE Program NCI Cancer Centers source: cancer.gov NCI CQIE – Centers of Quantitative Imaging Excellence Program

5. NCI – CQIE Program NCI Cancer Centers source: cancer.gov NCI CQIE – Centers of Quantitative Imaging Excellence Program

6. NCI – CQIE Program NCI Cancer Centers source: cancer.gov NCI CQIE – Centers of Quantitative Imaging Excellence Program

7. NCI – CQIE Program NCI Cancer Centers source: cancer.gov NCI CQIE – Centers of Quantitative Imaging Excellence Program

8. NCI – CQIE Program • Training to be “Trial-ready” • Scanning for Qualification NCI CQIE – Centers of Quantitative Imaging Excellence Program

9. NCI – CQIE Program • ACR CT Phantom Scans • CQIE Volumetric Protocol Scan (HRCT) NCI CQIE – Centers of Quantitative Imaging Excellence Program

10. NCI – CQIE Program • ACR MRI Phantom Scans • CQIE Volumetric Scan • Diffusion In Vivo Scan • DCE-MRI Brain • DCE-MRI Body NCI CQIE – Centers of Quantitative Imaging Excellence Program

11. NCI – CQIE Program • ACR Whole Body/Brain Scans • In Vivo test case • Uniform Phantom Whole Body/Brain/Dynamic Scans NCI CQIE – Centers of Quantitative Imaging Excellence Program

12. NCI – CQIE Program Site Qualification Process • Site Initiation Packet sent to site • Site submission of a CQIE Application • Execution of a participation agreement (MOU) • Submission of the Site Assessment Form • Completion of CQIE Web Learning Modules • Site Visit (first year) • MR/CT Site Visit (2 consecutive days, ~4 hours each) • PET Site Visit (~4 hours) NCI CQIE – Centers of Quantitative Imaging Excellence Program

13. NCI – CQIE Program Site Qualification Process (cont’d) • Qualification imaging is performed • Images and Data Form submissions • Evaluation of images and data (ACRIN) • Notification of results • Site compensation • Annual renewal (site responsibility!) NCI CQIE – Centers of Quantitative Imaging Excellence Program

14. NCI – CQIE Program Site Initiation NCI CQIE – Centers of Quantitative Imaging Excellence Program

15. NCI – CQIE Program Imaging NCI CQIE – Centers of Quantitative Imaging Excellence Program

16. NCI – CQIE Program Evaluation NCI CQIE – Centers of Quantitative Imaging Excellence Program

17. NCI – CQIE Program National Cancer Institute Roles: • Committed funding to support CQIE development of qualification guidelines and the process to qualify cancer centers • NCI will maintain oversight for the project • Will serve as a liaison to the cancer center community NCI CQIE – Centers of Quantitative Imaging Excellence Program

18. NCI – CQIE Program ACRIN Roles: • Development and dissemination of the CQIE qualification requirements and managing the qualification process • Maintain a Manual of Procedures (MOP) to serve as a resource for participating cancer centers • Develop and maintain the training curriculum • Provide assistance with obtaining phantoms NCI CQIE – Centers of Quantitative Imaging Excellence Program

19. NCI – CQIE Program • Administer a one-time payment to each CQIE qualified cancer center • Create a list of qualified CQIE sites that will be published on both the ACRIN and NCI web sites • At the direction of the NCI, perform annual requalification of participating institutions NCI CQIE – Centers of Quantitative Imaging Excellence Program

20. NCI – CQIE Program NCI CQIE – Centers of Quantitative Imaging Excellence Program

21. NCI – CQIE Program Site Roles • Cancer centers will need to execute the CQIE Memorandum of Understanding (MOU) • Each site is asked to identify a project leader to serve as the primary point of contact with ACRIN • Project leader will help coordinate and oversee the qualification activities at the site NCI CQIE – Centers of Quantitative Imaging Excellence Program

22. NCI – CQIE Program Site Roles • Active participation and an ongoing commitment from all three imaging modalities (MR, CT and PET). • Completion of on-line learning modules • Submission of the required test case images • CQIE specified phantom scans • Attest to required ongoing Quality Control (QC) activities NCI CQIE – Centers of Quantitative Imaging Excellence Program

23. NCI – CQIE Program Site Roles • Annual acquisition and submission of qualification imaging • Be committed to completing the qualification process expeditiously • Must agree to conduct annual requalification for 3 years NCI CQIE – Centers of Quantitative Imaging Excellence Program

24. NCI – CQIE Program ACRIN.ORG www.acrin.org/NCI-CQIE.aspx NCI CQIE – Centers of Quantitative Imaging Excellence Program

25. NCI – CQIE Program NCI CQIE – Centers of Quantitative Imaging Excellence Program

26. Jim Gimpel RT (R)(MR) Imaging Analyst ACR Clinical Research Center NCI CQIE – Centers of Quantitative Imaging Excellence Program