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Enabling Medical Experts to navigate clinical text for cohort identification (meTAKES). Stephen Wu, Mayo Clinic SHARPn Summit 2012 June 12, 2012. Outline. Motivation Methods (current) System architecture Data retrieval Search Cohort management Conclusion & Future Work. Motivation.
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Enabling Medical Experts to navigate clinical text for cohort identification (meTAKES) Stephen Wu, Mayo Clinic SHARPn Summit 2012 June 12, 2012
Outline • Motivation • Methods (current) • System architecture • Data retrieval • Search • Cohort management • Conclusion & Future Work
Motivation Somali patients (unique terms) Drug-induced liver injury (rel’ns) Pediatric asthma (temporal) • Clinical NLP out-of-the-box • Comprehensive knowledge • Customize? Collaborate! • Diverse requirements • Physician/Researcher tasks • Enroll patients in study • Define retrospective cohort • Case abstraction
“Medical expert”-driven NLP • Use case-agnostic • Comprehensive • Pre-computed NLP • Known requirements • Use case-specific • Streamlined • On-the-fly NLP • Diverse requirements • Interactive interface • Delivery mechanism • Available data vs. expert knowledge source text semantics expert criteria
Web interface (GWT) Client Server EHR data pool parameters GUI records NLP (MedTagger) query query parser cohort mgmt Lucene cohort manipulation records ranked records
Data retrieval • Parameters (current) • Patient ID • Date • Sources (current) • Enterprise Data Trust (EDT) @ Mayo Clinic • Text files on server
Search • Parameters (current) • Term lists • Logic • Expansion • Techniques (current) • Dictionary (Lucene) • NLP results (e.g., negation)
Cohort Management • Parameters: • Cohort name/tag • Selecting patients • Export • Iterative refinement
Conclusion and Future Work • NLP / search • Text characteristics • Semantic search • Relationships • HCI / cohort management • Learning • Collaboration • Interoperability • Structured data • API • Mayo delivery: DDQB Clinical Notes Search Tool Evaluation framework
meTAKES team: Stephen Wu Ravikumar K.E. Hongfang Liu Special thanks to: Siddhartha Jonnalagadda James Masanz Vinod Kaggal Sean Murphy Tom Suther Erik Voldal Carlos Garcia Melissa Gregg This work was supported in part by the SHARPn (Strategic Health IT Advanced Research Projects) Area 4: Secondary Use of EHR Data Cooperative Agreement from the HHS Office of the National Coordinator, Washington, DC. DHHS 90TR000201. https://sites.google.com/site/stephentzeinnwu wu.stephen@mayo.edu Thank you.