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Learn about nucleotides being the monomers of nucleic acids, their structures, roles as energy carriers and messengers, and the significance of DNA and RNA in heredity.
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3.6 What Are Nucleotides and Nucleic Acids? • Nucleotides are the monomers of nucleic acid chains and fall into two general classes • Deoxyribose nucleotides • Ribose nucleotides • All nucleotides are made of three parts • Phosphate group • Five-carbon sugar • Nitrogen-containing base
ATP-video-2:30-3:30DNA-video 2:00-305 • DNA- https://www.khanacademy.org/partner-content/crash-course1/crash-course-biology/v/crash-course-biology-110 • ATP https://www.khanacademy.org/partner-content/crash-course1/crash-course-biology/v/crash-course-biology-107
Nucleotides A. Structure • 5-C sugar • phosphate group • nitrogen-containing base • adenine • guanine • cytosine • thymine • uracil
Nucleotides: Deoxyribose and Ribose • Deoxyribose (A, G, C, T) 2. Ribose (A, G, C, U)
Nucleotides: Deoxyribose and Ribose • energy-carrier molecules • subunits of polymers called nucleic acids • intracellular messenger molecules
Nucleotides Act as Energy Carriers • ATP – adenosine triphosphate • ribose nucleotide • 3 phosphate groups • stores energy in bonds btwn phosphate groups • energy released when last phosphate bond is broken • available energy is then used to drive other rxns (linking amino acids)
How is ATP made and broken down? • 1. ADP + Energy + Phosphate -----> ATP • (stores energy) dehydration synthesis • ATP ------> ADP + Phosphate + Energy (releases energy) hydrolysis
Nucleotides Act as Intracellular Messengers • cAMP – ribose nucleotide cyclic adenosine monophosphate • messenger molecule in cells • hormones stimulate cAMP to form within cells where it initiates biochemical reactions • NAD+ & FAD – electron carriers • transport energy • in form of high- • energy electrons • used in ATP • synthesis NAD FAD
Nucleic Acids: DNA and RNA the Molecules of Heredity Nucleic acids: polymers made up of nulceotides (monomers) linked together via dehydrations synthesis found in chromosomes in cells
Figure 3-23 Deoxyribose nucleotide phosphate base sugar
Nucleotides: Deoxyribose and Ribose • Deoxyribose (A, G, C, T) 2. Ribose (A, G, C, U)
Figure 3-24 The energy-carrier molecule adenosine triphosphate (ATP)
3.6 What Are Nucleotides and Nucleic Acids? • Nucleotides act as energy carriers and intracellular messengers • Adenosine triphosphate (ATP) is a deoxyribose nucleotide with three phosphate functional groups • Ribose nucleotide cyclic adenosine monophosphate (cAMP) acts as a messenger molecule in cells • Electron carriers are those nucleotides (NAD and FAD) transporting energy in the form of high-energy electrons
3.6 What Are Nucleotides and Nucleic Acids? • DNA and RNA, the molecules of heredity, are nucleic acids • Nucleic acids are polymers formed by monomers strung together in long chains by dehydration synthesis
3.6 What Are Nucleotides and Nucleic Acids? • DNA and RNA, the molecules of heredity, are nucleic acids (continued) • There are two types of polymers of nucleic acids • DNA (deoxyribonucleic acid) is found in chromosomes and carries genetic information needed for protein construction • Each DNA molecule consists of two chains of nucleotides that form a double helix linked by hydrogen bonds • RNA (ribonucleic acid) makes copies of DNA and is used directly in the synthesis of proteins
Figure 3-25 Deoxyribonucleic acid hydrogen bond