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Is the abdominal pressure - inflated volume relation linear?. Jan Paul Mulier, MD PhD (1), Bruno Dillemans, MD (2) Department of Anaesthesiology Department of surgery, AZ Sint-Jan AV Brugge, Belgium. Goal of the Study.
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Is the abdominal pressure - inflated volume relation linear? Jan Paul Mulier, MD PhD (1), Bruno Dillemans, MD (2) Department of Anaesthesiology Department of surgery, AZ Sint-Jan AV Brugge, Belgium Goal of the Study A pneumoperitoneum with CO2 allows the measurement of the pressure-volume relation (APVR). Is a linear fit (y=mx+b) sufficient as a description? Mulier Linearity of the abdominal P-V relation
Methods and Analysis • 30 patients, ASA class I, II or III, 21 to 75 years, • No previous abdominal intervention. • Scheduled for a laparoscopic surgery. • Approved by the hospital ethical committee. • Anaesthesia was induced with Propofol 200 mg, Sufentanil 20 ug, Nimbex 0,2 mg/kg and Sevoflurane 1,5 Mac in a 50 % O2/N2O. • Bladder empty before surgery. • Stomach emptied by suction through a gastric tube. • All the CO2 was allowed to escape after insertion of the trocar. • An Olympus insufflator UHI-3 gives a stepwise flow of 1 l/min • Measurements were taken every 100 ml till the abdominal pressure reached 15 cmH20. • APVR data were fit by a linear least-squares regression. • An r2 of 0.95 is assumed to be sufficient. Mulier Linearity of the abdominal P-V relation
Results and Discussion A graph shows the APVR and the fitting of the first 10 patients. The table shows the mean and stdv of 30 patients for two parameters a and b with r2 A first order fit is sufficient. Mulier Linearity of the abdominal P-V relation
Conclusion • A linear relation fits all APVR data sufficient. • The abdominal pressure inflated volume relation behaves linear with an elastance and a pressure at zero volume. • This between 0 and 15 cmH20, the pressures used for laparoscopy. Mulier Linearity of the abdominal P-V relation