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LSD and mescaline (Hallucinatory)

LSD and mescaline (Hallucinatory). B9902010 左華韋 B9902035 洪昌宏. Hallucinogen. Can cause subjective changes in perception , thought , emotion and consciousness . Cause non-ordinary forms of consciousness such as trance ( 恍惚 ) , meditation ( 冥想 ) , and dreams ( 幻想 ).

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LSD and mescaline (Hallucinatory)

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  1. LSD and mescaline (Hallucinatory) B9902010 左華韋 B9902035 洪昌宏

  2. Hallucinogen • Can cause subjective changes inperception, thought, emotionand consciousness. • Cause non-ordinary forms of consciousness such as trance(恍惚) , meditation(冥想) , and dreams(幻想). • Psychedelics • Dissociatives • Deliriants

  3. Hallucinogen • 改變思想、知覺、情緒是其主要效果 • 幾乎不會影響智力或造成記憶障礙 • 不會造成昏迷、麻醉 • 不會對自律神經系統產生副作用 • 不具有成癮性

  4. Psychedelic drug • Ergolines • tryptamine -based compounds • phenethylamine -based compounds(苯乙胺化合物) • Serotonergic psychedelics (serotonin 5-HT2A receptor agonists)

  5. 5-HT2Areceptor •  血清素（情緒物質）受體 ，調節濃度 • G protein-coupled receptor(GPCR) • 與精神疾病有關 • 尤其於視覺皮層與前額 　皮層特有作用

  6. 血清素 • 神經傳導物質 • 與人類情緒有關 • 癌細胞抑制者

  7. LSD • Lysergic acid diethylamide • Dosage：100-500μg • Hightolerance

  8. Effects • Physical • 共通：瞳孔擴大、降低(或增加)食慾、提神。 • 個別：乏力、噁心、體溫改變、心跳加速、盜汗、失眠、顫抖……等等。

  9. Effects • Psychological • “Trip” • “Walls breathing“ • Colored patterns behind the closed eyelids. • Altered sense of time.

  10. mescaline • 仙人掌種籽、花粉中提取出來 • 無成癮性 • LD50：328mg/kg • Mescaline比LSD效用弱約4000倍

  11. Effects • Normal coordination and reflexes are reduced • less disorienting • rapid changes in mood, feelings • spiritual experiences

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