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Oral Abstract TUPDC0302 XIX International AIDS Conference Washington, DC, USA July 24, 2012

Perceptions and Attitudes about Pre-exposure Prophylaxis ( PrEP ) among Seronegative Partners and the Potential of Sexual Disinhibition Associated with the Use of PrEP. Avnish Tripathi MD, MPH 1 ; Y. Omar Whiteside PhD, MPH 1 ; Christopher Scanlon BSc 2 ; Wayne A. Duffus MD, PhD 2

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Oral Abstract TUPDC0302 XIX International AIDS Conference Washington, DC, USA July 24, 2012

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  1. Perceptions and Attitudes about Pre-exposure Prophylaxis (PrEP) among Seronegative Partners and the Potential of Sexual Disinhibition Associated with the Use of PrEP AvnishTripathi MD, MPH1; Y. Omar Whiteside PhD, MPH1; Christopher Scanlon BSc2; Wayne A. Duffus MD, PhD2 1Arnold School of Public Health, University of South Carolina, Columbia, SC; 2Department of Health and Environmental Control, Columbia, SC Oral Abstract TUPDC0302 XIX International AIDS Conference Washington, DC, USA July 24, 2012

  2. Objectives/Methods • To explore the perceptions and attitudes about PrEP among both MSM and heterosexual seronegativepartners • A pilot, self-administered survey was conducted, in 2010-2011, among seronegative partners of patients attending a Ryan White clinic in Columbia, SC who were: • ≥ 18 years • Reported at least six months of stable relationship • The survey gathered information about demographics; sexual behavior and HIV risk factors; knowledge about HIV transmission; and perception and attitude about the potential future use of PrEP

  3. Results • A total of 89seronegative partners completed the survey • The median age was 42 years (IQR: 32-50) and majority were males (56%), non-Hispanic black (70%), heterosexual (74%), had a secondary education or lower (65%), and monthly income of ≤ $1500 (58%) • Only 58%reported always (100%) using condoms during vaginal or anal intercourse after learning their HIV seropositive partner’s status and 72%reported using condoms during their last vaginal and/or anal sexual intercourse with their primary partner • Majority (94%) were willing to use PrEP, if available. • However, 26%suggested that they would be more likely to have unprotected sex with HIV-positive partners and 20%with a new partner while using PrEP. In addition, 27%suggested that it would be difficult to take daily dose of PrEP and also consistently use condoms.

  4. Conclusions • There is high acceptability and interest among seronegative partners to use PrEP to lower the risk of HIV transmission • However, there is the potential risk of sexual disinhibitionwhile using PrEP • Decreasing the potential for such behavior may require increased provider comfort at sexual history taking and offering continual risk reduction counseling

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