Introduction and Welcome

1. Introduction and Welcome Joel Saltz MD, PhD Co-Director caGrid Knowledge Center caGrid Knowledge Center Workshop February 2011

2. caGrid Knowledge Center • Design, development, use of Biomedical Informatics Middleware • Internal and Collaborative testing, prototyping • Example areas: methods to reduce introduction of errors in federated data sources, common data element representation and management, management and query of Pathology/Radiology annotation, markup data, semantically enhanced ETL

3. Broad Community Interaction • Broad and Ongoing Interaction with application communities – examples: • CTSA – multiple prototypes, SOA working group • NCRI – conferences, caGrid based collaborations • Cardiovascular Research Grid – middleware framework that incorporates caGrid components • Minority Health Grid – Difficult to treat hypertension in young African American men - whole exome sequencing

4. Broad Community Interaction • Radiation Therapy Oncology Group, Advanced Technology Consortium, Quantitative Imaging Network - caGrid data, metadata, service federation • ACRIN – Support for management of imaging annotation, markup data • In silico centers – Science driven by integration of Imaging, Pathology, “omic”, outcome data. • Novartis – Use of caGrid components

5. caGrid Experience Panel this afternoon • Wealth of experience here • Panel this afternoon with UAB, Utah, Roswell Park, Chronic Lymphocytic Leukemia Research Consortium, CVRG, ACTSI and TRIAD • Initial Questions : • List three additions/modifications to caGrid that, if carried out, would have made your project easier to accomplish • List three additions/modifications to caGrid that, if carried out, would have allowed you to make your project more effective • If you had to redeploy your project without using caGrid, what software would you use and how would this alternate software stack impact your project. • How can NCI and/or Grid KC better support caGrid 1.x?