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Patterns of Inheritance . Mutations . Mutation: change in the nucleotide-base sequence of a gene or DNA molecule Occur infrequently due to natural and environmental factors Faulty replication Ionizing radiation = x-rays. Somatic or sex cell mutations . Inherited : mutation in gamete
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Mutations • Mutation: change in the nucleotide-base sequence of a gene or DNA molecule • Occur infrequently due to natural and environmental factors • Faulty replication • Ionizing radiation = x-rays
Somatic or sex cell mutations • Inherited : mutation in gamete • Sickle cell anemia • NOT inherited : mutation in body cell • Golden delicious apples • Golden color in wall of flower
Mutations Chromosome Deletion Inversion Translocation Nondisjunction
Point mutation= a nucleotide is added, removed, or changed Frameshift = addition or deletion causes the DNA to shift a frame ( Codons)
Pedigrees With disease Male I Not w/disease Female II III
Autosomal Dominant: State if the pedigree is true or false • If neither parent has the Autosomal trait, the offspring won’t receive it. • If both parents have the trait, the offspring might not get it.
Autosomal Recessive: State if the pedigree is true or false • If neither parent has the disease, it is possible for the offspring to have it.
X-linked traits State if the pedigree is true or false • An infected male can not pass the trait to his son. • An affected mother can not pass it to a daughter if the father is not affected.