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5 ' UTR Modeling

5 ' UTR Modeling. Sam Gross Randy Brown. TWINSCAN Accuracy NCBI34 Chromosome 7. Old 5 ' UTR Model. Einit. Inter. Utr5. Prom. Esngl. Prom. ATG. Coding Exon. Inter. Utr5. New 5 ' UTR Model. Enc. Inc. Ep. Einit. Ea. Inter. Prom. Epa. Esngl. Prom. Epa. ATG. Coding Exon.

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5 ' UTR Modeling

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  1. 5' UTR Modeling Sam Gross Randy Brown

  2. TWINSCAN Accuracy NCBI34 Chromosome 7

  3. Old 5' UTR Model Einit Inter Utr5 Prom Esngl Prom ATG Coding Exon Inter Utr5

  4. New 5' UTR Model Enc Inc Ep Einit Ea Inter Prom Epa Esngl Prom Epa ATG Coding Exon Inter Prom Ep Ea ATG Coding Exon Inter Inc Prom Ep Enc Ea ATG Coding Exon Inter Inc Inc

  5. Length Distributions • Inc, Ea states use geometric length distributions • Epa, Ep, Enc states use distribution P(x) = AxNe-x/

  6. Effect Of New 5' UTR Model On Accuracy

  7. Future Directions • Test accuracy of 5' UTR predictions • 5' UTR “coding” model • New promoter model

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