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Organ Transplants. A Scientific Approach. Donor/Recipient Matching. Testing Location Size of Organ Time Spent Waiting Condition of Recipient. Blood Typing. Confirms blood type depending on certain antigens. Tests ABO Typing Back Typing Types A, B, AB, O Rh +, Rh -. Tissue Typing.
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Organ Transplants A Scientific Approach Ashley Seal
Donor/Recipient Matching • Testing • Location • Size of Organ • Time Spent Waiting • Condition of Recipient Ashley Seal
BloodTyping Confirms blood type depending on certain antigens. Tests ABO Typing Back Typing Types A, B, AB, O Rh+, Rh- Ashley Seal
Tissue Typing Serum Platelet Antibody Test Cell Bound Platelet Antibody Test HLA-B27 Test Narcolepsy – Associated Antigen Test HLA Class I and HLA Class II Molecular Typing Granulocytic Antibody Test Ashley Seal
Organ Size • Recipient/donor weight ratio of less than a 7.5 ratio in kidneys has not shown to impact function • Testing lung capacity in lung transplant patients has shown to be an accurate determination of size Overall organ size is hard to determine. Each organ uses different techniques when determining size Ashley Seal
Other Factors: Assuming there is a match • Location: Closer to the donor organ, the better • Time: The longer a prospective recipient has been on the waiting list increases the chance that he or she will receive an organ • Condition of the recipient: The surgeon of the patient will make the over all decision of whether to accept the donor organ or not based on the current health of the patient while also considering patient history Ashley Seal
Sources • http://www.nlm.nih.gov/medlineplus/ency/article/003345.htm • http://www.mayomedicallaboratories.com/about/services/tissuetyping.html • http://www.transplantliving.org/beforethetransplant/qa.aspx#matchFactors • http://optn.transplant.hrsa.gov/about/transplantation/transplantProcess.asp • http://www.ncbi.nlm.nih.gov/pubmed/20098284 • http://optn.transplant.hrsa.gov/about/transplantation/matchingProcess.asp • http://www.ncbi.nlm.nih.gov/pubmed/19379997 Ashley Seal