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BIOLASE. THE INNOVATIVE, RESEARCHED AND PATENTED IMMUNO-MODULATOR FOR ALL MONOGASTRICS. BIOLASE. THE SYMBIOTIC. INTESTINAL MICROBIAL FLORA (MONO GASTRIC). GRAM POSITIVES STREPTOCOCCUS LACTOBACILLUS BIFIDOBACTERIUM EUBACTERIUM PEPTO-STREPTOCOCCUS. GRAM NEGATIVES CLOSTRIDIUM
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BIOLASE THE INNOVATIVE, RESEARCHED AND PATENTED IMMUNO-MODULATOR FOR ALL MONOGASTRICS
BIOLASE THE SYMBIOTIC
INTESTINAL MICROBIAL FLORA(MONO GASTRIC) GRAM POSITIVES • STREPTOCOCCUS • LACTOBACILLUS • BIFIDOBACTERIUM • EUBACTERIUM • PEPTO-STREPTOCOCCUS • GRAM NEGATIVES • CLOSTRIDIUM • VEILLONELLA • ENTEROBACTERIACEE YEASTS (less than 0.1%)
STREPTOCOCCUSfaecium LACTOBACILLUS acidophilus, fermentum, salivarius, animalis, reuteri BIFIDOBACTERIUM Globosum, pseudologum, animalis, thermophilum, boum, magnum, pullorum, suis, cuniculi, choerium. (Sneath P.H.A., et all. 1986)
INTERACTION MICROORGANISM / SURFACE INTERACTION MICROORGANISM/ RESISTANCE INTESTINAL MICROBIAL FLORA 2 PRIMARY FUNCTIONS:
Interaction MICROORGANISM/ SURFACE • PROTEOLYTIC ACTION • UROLYTIC ACTION
Interaction MICROORGANISM/RESISTANCE • ORGANIC ACID PRODUCTION (Acetic and Lactic, mostly) • Antibacterial effect • Lower ammonia absorption • Lower amines absorption
Interaction MICROORGANISM/RESISTANCE • Immunological activation • Production of Vitamins and Enzymes • N-nitrosamines Degradation • Reduction of Ammonia and Hydrogen Sulphide. • Production of bactericidal substances • (self regulation)
INTESTINAL ECO-SYSTEM STABILITY BALANCE
LIVE LACTOBACILLI/STREPTOCOCCI ADMINISTRATION • Sensitive to chemical & physical stress (heat, pH,…) • Slow growth (6-8 hours) • BIO-TYPE BIFIDOBACTERIUM ORAL ADMINISTRTATION IMPOSSIBLE: • ANAEROBES
LIVE YEASTS Naturally: • Acid resistant • pH resistant • Antibiotic resistant
LIVE YEAST • LIVE ORGANISM (ANIMAL) • CONSUMES • PRODUCES CARBOHYDRATES / SUGARS ALCOHOL – CARBON DIOXIDE (BREWERY) ( BAKERY)
DEAD YEAST - DRIED-UP YEAST- • BY-PRODUCT OF BREWERY INDUSTRY • SOURCE OF PROTEIN • ALL NUTRIENTS ALREADY USED UP • DOSAGE 5-10 Kg/Ton
BIOLASE NO MORE ALIVE • DOES NOT FERMENT • DOES NOT REPRODUCE • DOES NOT PRODUCE ALCOHOL • DOES NOT PRODUCE CARBON DIOXIDE THE CELL IS WHOLE • VITAMINS • ENZYMES • NUCLEOSIDES • NUCLEOTIDES
BIOLASE BIO-ACTIVITY CAN BE MEASURED CAPACITY TO MAKE A LACTOBACILLI&BIFIDA POPULATION GROW MORE THAN A CONTROL GROUP BIOLASE BIO-ACTIVITY: MIN. 4.5
IN VITRO BIO-ACTIVITY TEST (INCUBATION TIME: 8 hours – temperature: 37°C) GROWTH
BIOLASE BIOACTIVITY BIOLASE CONTROL 30 Growth curves of 2 lactobacilli coltures, incubated at 37°C. After 5 hours you have BIOLASE highest bioactivity , as expression of the ratio between the two coltures growth levels (measured as Optical Density) 20 OPTICAL DENSITY 10 0 1 2 3 4 5 6 7 INCUBATION (HOURS)
“digesting” BIOLASE cells Bifida
“eating” Lactobacilli a BIOLASE cell
“digesting” BIOLASE cells Bifida
Tadpoles The one on the right has been fed BIOLASE
Lactobacilli Population (white) attacked by pathogenes (black)
Lactobacilli&Bifida population has grown stronger and larger, thanks to BIOLASE
BIOLASE is the ideal nutrient for Lactobacilli&Bifida growth