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Complex Traits of Heredity Chpt . 12

Complex Traits of Heredity Chpt . 12. Recall Simple Types of Heredity. Recessive  Recall, must have both recessive alleles ( aa ) to have a recessive trait. Autosomal (Complete) Dominance  Recall, only 1 allele needed to have a dominant trait (AA or Aa ) .

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Complex Traits of Heredity Chpt . 12

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  1. Complex Traits of Heredity Chpt. 12

  2. Recall Simple Types of Heredity Recessive  Recall, must have both recessive alleles (aa) to have a recessive trait Autosomal (Complete) Dominance  Recall, only 1 allele needed to have a dominant trait (AA or Aa)

  3. Complex Patterns of Inheritance

  4. Complex Traits • Simple Mendelian genetics does not explain most traits • For example: There are at least 8 different genes associated with eye color so it isn’t so cut and dry like Mendel’s pea plants!!

  5. CodominanceBoth Alleles Expressed Together

  6. Below; Both Pigmented (Red) and Non-Pigmented (White) Both the pink and the white alleles are expressed in the heterozygote **RR=Red **W W= White **RW (Heterozygous) ~~~displays BOTH Red AND white alleles!!

  7. Codominance in Animals ** Example: When a red horse is crossed with a white horse, a roan horse is produced. The phenotypes are: Red (RR) White (WW) Roan (RW) Heterozygous Red and White (Hybrid) Occurs in cows too!!!

  8. CodominantPunnett Square Roan Cow (RW) Roan Bull (RW) R W R W RR 1Red:2Roan:1 White 25% Red 25% white 50% Roan (red AND White) R R W WW W

  9. Who’s the Father of the Calves….Codominance Mystery!!!

  10. Incomplete Dominance – two phenotypes create a heterozygote that is intermediate between each of them; A blending of the two phenotypes to create a third phenotype Heterozygous/Hybrid Intermediate R’R R’R R’R’ RR WHITE PINK RED USE PRIMES ABOVE THE ALLELE (LETTER) FOR LACK OF PIGMENTATION…

  11. Incomplete Dominance Wavy Hair Intermediate Phenotype H’H (Heterozygous) Straight Hair H’H’ Curly Hair HH

  12. Incomplete Dominance – Hair A couple, both with wavy hair, want to have a baby. What are the genotypic and phenotypic ratios of their possible offspring?? H H’ Genotypic Ratio: 1HH:2H’H:1H’H’ H HH H’H Phenotypic Ratio: 1Curly:2Wavy:1Straight H’ H’H H’H’

  13. X-Linked (sex linked) Traits/Disorders/Conditions

  14. X-linked Traits If a Recessive Trait: XNXN = Normal female XNXn = Normal Carrier XnXn Affected female • XNY= Normal Male • XnY=Affected Male • Males can NEVER be carriers!!!!

  15. Colorblindness Is Recessive and On the X Chromosome

  16. Hemophilia:sex-linked recessive trait. If affected, lack a blood clotting factor. • May die from a cut if left untreated • Treatment entails giving the person the clotting factor by injection

  17. X-linked – REMEMBER NO SUPERSCIPTS ON Y CHROMOSOME!!! If a man is colorblind and has a child with a heterozygous female carrier………What is Dad’s genotype? Mom’s? XnY XN Xn 1 of 2 Daughters or 50% of the girls 1. Probability of a Colorblind Daughter?? Xn Y XN Y XN XN Xn 1 of 2 Sons or 50% of the boys 2. Colorblind Sons?? 3. Out of ALL of the children, how many are carriers?? Xn XnXn • XnY ONLY1 ofthe four Children… Why? Males only have 1 X!! Can’t Carry on the Y….this is X-Linked!!!

  18. Polygenic Traits – 2 or more genes affect one phenotype **Polygenic traits follow a normal distribution, bell curve based on an average of a population Examples: hair color, eye color, height

  19. Notice the Difference in Brightness!! Light Colors to Dark Colors!!

  20. A simplified model for polygenic inheritance of skin color ** Polygenic traits in a population typically follows a bell curve; lightest skin color to the left of the curve and the darkest to theright……Notice the majority of the population is a medium tone

  21. Multiple Alleles – 3 or more forms of a genes (alleles) involved in ONE trait In the hypothetical family above, there are 6 alleles for one trait

  22. Blood Types are controlled by threealleles….…A,B and O

  23. Blood Types – Multiple Alleles Phenotype Genotype Type A IAIA or AA (homozygous A) or IAior AO (heterozygous A) Type B IBIB or BB (homozygous B) or IBi, BO (heterozygous B) Type AB IAIB,or AB Codominant!! Type O ii or OO  Recessive

  24. Example of a punnett square of a Heterozygous Type A father and Type O mother.

  25. Practice Punnett Squares – Cross the Following: • A homozygous Type A female with a Type O male • A Type AB male with an O female • A heterozygous Type B male with a heterozygous A female • A couple that are both type AB

  26. Environmental Influences and Genetics

  27. External Factors and Internal Factors • Temperature, nutrition, light, chemicals, hormones, age, can influence gene expression.

  28. External Factors • In arctic foxes temperature has an effect on the genetic expression of coat color seasonally.

  29. External Factors • Leaves can have different sizes, thicknesses, and shapes depending on the amount of light they receive.

  30. Internal Factors • Males and females differ in hormones and structural differences • can cause a single genotype to express more than one phenotype (antlers in males)

  31. Internal Factors • An organism’s age can also affect gene function. • Random mutations can accumulate • Organ function diminishes

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