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Pharmacology Review: Key Drugs & Mechanisms

Updated review covering principles of pharmacology & cardiovascular, respiratory drugs. Essential insights into major drug classes, mechanisms of action, and clinical applications.

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Pharmacology Review: Key Drugs & Mechanisms

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  1. 2004-2005Pharmacology Reviewof Everything(Principles, Cardiovascular and Respiratory drugs have been updated) 21 December 20192:12 AM

  2. Methenamine • Urinary tract antiseptic • Decomposes to formaldehydein acidic environment

  3. Methicillin • Penicillin antibioticCell wall synthesis inhibitor • Pencillinase resistant penicillin Inhibits peptidoglycan cross-linking

  4. Methimazol • Antithyroid • Prevents synthesis ofthyroid hormones(blocks iodine organification)

  5. Methotrexate • ImmunosuppressiveAntineoplastic • Folic acid antagonistDihydrofolate reductase inhibitor

  6. Methoxamine • Sympathomimetic1adrenergic agonist • Vasoconstrictor

  7. Methylcellulose • Bulk laxative

  8. Methydopa • Sympatholytic2adrenergic agonist • Antihypertensive

  9. Methylphenidate • Indirect sympathomimeticDrug of abuse • ADD treatmentStimulant

  10. Methylprednisolone • AdrenocorticosteroidGlucocorticoid • Anti-inflammatory steroidNot by inhalation

  11. Methyltestosterone • Androgen • Synthetic oral

  12. Metipranolol • Sympatholytic adrenergic antagonist • Bronchoconstrictor

  13. Metoclopramide • Prokinetic agentAntiemetic • D2 antagonist

  14. Metocurine • Paralytic • Paralyzes skeletal muscles

  15. Metolazone • Thiazide-like diuretic • Na-Cl symporter inhibitorAntihypertensive

  16. Metoprolol • Sympatholytic1adrenergic antagonist • AntihypertensiveHeart failure medicationBronchoconstrictor

  17. Metronidazole • AntibioticAntiparasiticAntiulcer • AnaerobesReduction leads to intermediatesthat damage DNA

  18. Metyrapone • Glucocorticoid antagonist

  19. Mexilitine • Class I antiarrhythmic • Na+ channel blocker(activated and inactivated channels)

  20. Miconazole • Imidazole antifungal • Inhibits synthesis of ergosterol by inhibiting lanosterol 14a demethylase

  21. Midazolam • Sedative hypnotic • Short-acting benzodiazopine

  22. Mifepristone(RU-486) • Progesterone antagonist

  23. Miglitol • Oral hypoglycemic • Alpha-glucosidase inhibitorInhibits intestinal glucose absorption

  24. Mineral oil • Lubricating laxative • Stool softener

  25. Minocycline • Tetracycline antibioticBacteriostatic protein synthesis inhibitor • 30S ribosomePrevents aminoacyl tRNA attachment

  26. Minoxidil • Vasodilator • Antihypertensive

  27. Misoprostol • ProstaglandinAntiulcer

  28. Mitomycin C • Antineoplastic • Natural productAntibiotic

  29. Mivacurium • Paralytic • Paralyzes skeletal muscles

  30. Moezipril • Antihypertensive • Converting enzyme inhibitor

  31. Montelukast • Leukotriene inhibitor • LTR1 and LTD4 antagonistAsthma treatment

  32. Moricizine • Class I antiarrhythmic • Na+ channel blocker

  33. Morphine • OpioidAnalgesic •  receptor agonist

  34. Muromonab-CD3 • Immunosuppressive • Mouse monoclonal anti-CD3 antibody Organ transplant (anti-rejection)

  35. Mycophenolate • Immunosuppressive • Inhibits inosine monophosphate dehydrogenase activity

  36. Nadolol • Sympatholytic adrenergic antagonist • Antihypertensive

  37. Nafarelin • Gonadotropin releasing hormone (GnRH) agonist

  38. Nafcillin • Penicillin antibioticCell wall synthesis inhibitor • Penicillinase resistant penicillinInhibits peptidoglycan cross-linking

  39. Nalbuphine • Opioid antagonist •  receptor antagonist

  40. Nalidixic acid • Urinary tract antiseptic • QuinoloneInhibits bacterial DNA gyrase

  41. Nalmefene • Opioid antagonist

  42. Nalorphine • Opioid antagonist

  43. Naloxone • Opioid antagonist

  44. Naproxen • NSAIDAnalgesic, Anti-inflammatory, Antipyretic • Cyclooxygenase inhibitor

  45. Nateglinide • Oral hypoglycemic • MeglitinideInsulinotropic

  46. Naltrexone • Opioid antagonist

  47. Nedocromil • Mast cell stabilizer • Inhibits release of mast cell mediatorsUsed prophylactically in asthma

  48. Neomycin • Aminoglycoside antibioticBactericidal protein synthesis inhibitor • 30S ribosomeFreezes initiationTopical

  49. Neostigmine • Anticholinesterase • VasodilatorTreatment for myaesthenia gravisPromotes defecation and urinationBronchoconstrictor

  50. Netilmicin • Aminoglycoside antibioticBactericidal protein synthesis inhibitor • 30S ribosomeFreezes initiation

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