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A Multilingual , Relational Database of Health Evidence

A Multilingual , Relational Database of Health Evidence. Gabriel Rada, Daniel Capurro, Daniel Perez Epistemonikos foundation. Episte … what ?. EPISTEMONIKOS ( ΕΠΙΣΤΗΜΟΝΙΚΟΣ  ) What is worth knowing. Who we are. Epistemonikos is a nonprofit organization based in Santiago, Chile

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A Multilingual , Relational Database of Health Evidence

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  1. A Multilingual, RelationalDatabase of HealthEvidence Gabriel Rada, Daniel Capurro, Daniel PerezEpistemonikos foundation

  2. Episte…what? EPISTEMONIKOS(ΕΠΙΣΤΗΜΟΝΙΚΟΣ ) Whatisworthknowing

  3. Whowe are Epistemonikos is a nonprofitorganizationbasedin Santiago, Chile Ourmissionis“tobringhighqualityinformationclosertohealthdecisionmaking”

  4. Theproblem: informationoverload New oral anticoagulants in atrial fibrillation

  5. Theproblemisyoudontknowthesecrets of PubMed ("Atrial Fibrillation"[Mesh] OR "Atrial Flutter"[Mesh] OR ((atrial OR auricular) AND (fibrillation* OR flutter*)) OR AF[Text Word]) AND ("Factor Xa/antagonists AND inhibitors"[Mesh] OR ((factor xa OR factors 10a OR fXa OR autoprothrombin c OR thrombokinase) AND inhibit[Text Word]) OR (activated AND (factor x OR factors 10) AND inhibitor*) OR xabans[Text Word] OR (antistasin OR apixaban OR betrixaban OR du 176b OR eribaxaban OR fondaparinux OR idraparinux OR otamixaban OR razaxaban OR rivaroxaban OR aygin OR ym 150 OR ym150 OR LY517717 OR darexaban OR edoxaban OR SSR126517E) OR ((dabigatran OR BIBR1048) OR ximelagatran OR AZD0837))

  6. Oooops… ..butyou can search “systematicreviews” [bestevidence]

  7. Muchbetter, ah? Yoy can startreading …see ya!

  8. Wake up!!! Youhavetoreadthem, compare whichstudiestheyinclude ….and begthey are wellconducted, saythesamething and addressthesamestudies. Out of bed, sleepyhead!!! 8 systematicreviewsfor my question

  9. Thechallenge: toseparatethewheatfromthechaff 23,000,000 records only in PubMed • 0,25% are systematicreviews

  10. Ourgoal TO AGGREGATE ALL THE RELEVANT HEALTH EVIDENCE (FOR DECISION-MAKING) INTO A SINGLE DATABASE.

  11. www.epistemonikos.org • Free • Released 1 yearago

  12. Multilingual interface • Multilingualsearch • Translations of abstracts

  13. Whatevidence? Systematicreviews Overviews of reviews High-qualitystructuredsummaries Primarystudiesincluded in systematicreviews

  14. Systematicreviews (SR) at the centre • Theaverage SR takesabout 1-year of work • Werescuethateffortbystoringidentifiedstudies From: http://www.navigatingeffectivetreatments.org.au/understanding_systematic_reviews.html The Centre for Health Communication and Participation with support from the Australasian Cochrane Centre

  15. Allthateffortinto a single database

  16. Ifthereviewersfoundit, we’vegotit Unpublished!!!

  17. Where do wesearch?  19 databases

  18. How do wefeed Epistemonikos? • Combination of machine technology and humancollaboration

  19. 1 Automaticsearch and upload 2 Selection of actual systematicreviews by a network of collaborators 3 Extractionof thestudiesincluded in thesystematicreview

  20. ADDED VALUE Notjust records RELATIONS ADDITIONAL DATA (metadata) RECORDS(Studies, reviews, overviews) TRANSLATIONS VISUALIZATION

  21. Relations are stored in thedatabase

  22. New anticoagulantsfor atrial fibrillation

  23. Thenumbers • 158,211 records • 30,651 systematicreviews • Theworld’sbiggestcollection of certifiedsystematicreviews • 109,889 primarystudies • +200 collaborators

  24. How Epistemonikos compares toexistingresources? Notjust records Other 16 databases ADDED VALUE RELATIONS ADDITIONAL DATA (metadata) Dare Cochrane TRANSLATIONS VISUALIZATION Epistemonikos Pubmed

  25. Let’ seeanexample New oral anticoagulants in atrial fibrillation

  26. Alltheevidence (systematicreviewsand studies) forourquestion*Thematrix of evidenceisexpectedtobereleased at theend of thisyear

  27. Conclusions • One-stop shop forevidence • Multilingualdatabase • Userfriendly • Relationbetweenarticlesanswering a similar question • Visualisation of ‘alltheevidence’ for a specificquestion

  28. Manythanks!!Contactus: contact@epistemonikos.org radagabriel@epistemonikos.org …orfollowus in yourpreferredlanguage: • English: @epistemonikos • Spanish: @epistemonikosEs • German: @epistemonikosDe • French: @epistemonikosFr • ….also in Facebook and google+ • Portuguese: @epistemonikosPt • Italian: @epistemonikosIt • Arabic: @epistemonikosAr • Dutch: @epistemonikosNl • Chinese: @epistemonikosZh

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