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Supplementary Figure S1. Chicago Head and Neck Cancer Genomics Cohort (CHGC). HNSCC tissue extraction ( n=120 ) RNA/DNA/Protein Tumor content ≥ 60%. Next gen sequencing (n=120, Agilent CGH Capture ). HPV Consensus Testing ( n=120 ). Copy number (CONTRA). Mutation ( Mutect ).
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Supplementary Figure S1 Chicago Head and Neck Cancer Genomics Cohort (CHGC) HNSCC tissue extraction (n=120)RNA/DNA/Protein Tumor content ≥ 60% Next gen sequencing (n=120, Agilent CGH Capture) HPV Consensus Testing (n=120) Copy number (CONTRA) Mutation(Mutect) Recurrent CN (Gistic-like strategy) Recurrent somatic mutation (Mutsig) CN validation • (n=81, Nanostring) • Mutation validation (n=120, NimbleGen EZ Choice capture )