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HFOV high frequency Oscillatory Ventilation. Becky Varela & Jamie Wood. Overview. High Frequency Ventilation (HFV) High Frequency Oscillatory Ventilation (HFOV) and h ow it works When do we use HFOV Basic Parameters for HFOV How HFOV prevents Ventilator Induced Lung Injury (VILI).
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HFOVhigh frequency Oscillatory Ventilation Becky Varela & Jamie Wood
Overview • High Frequency Ventilation (HFV) • High Frequency Oscillatory Ventilation (HFOV) and how it works • When do we use HFOV • Basic Parameters for HFOV • How HFOV prevents Ventilator Induced Lung Injury (VILI)
High Frequency Ventilation • Provides augmented gas distribution • By means of numerous gas transport mechanisms. • Convection, transit time, direct ventilation • Pendalluft effect • Taylor dispersion • Asymmetric velocity • Cardiogenic Mixing • Molecular diffusion • Collateral Ventilation
Convection • is the transport ofair flow at a constant equal velocity that is parabolic in shape. • Transit Time: • Airflow to the alveoli will vary in proportion to the length of the Bronchial airways. • Direct Ventilation: • Results from bulk air flow to alveoli that have a much shorter transit time.
Asynchronous Filling • At the end of expiration: • Alveoli with short time constants (fast alveoli units) are empty. • Alveoli with longer time constants (slow alveoli units) are still emptying • Asynchronous filling: • Gases will move from slow units to fast units because of pressure gradients between the alveoli. • The relationship between: • Axial velocity profile (Turbulence) • the diffusion of gases in motion • and the branching network of the lungs.
Airflow moving through the airways moves in a u-shape formation. At the center of the lumen air will move at a faster velocity, than air that is closest to the wall. Asymmetry Occurs with rapid respiratory cycles. Gases (O2) at the center of the lumen will advance further into the lungs as gases (CO2) along the wall of the airway moves out towards the mouth. As the heart beats the heart provides additional peripheral mixing by exerting pressure against the lungs during contraction of the heart. This pressure promotes the movement of gas flow through the neighboring parenchymal regions.
Maintaining a constant distending pressure with HFV within the lungs along with movement of gas molecules promotes gas diffusion across the alveolar membrane, at a faster rate. • Collateral ventilation increases with HFV due to connections between the alveoli • (Pores of Kohn)
How does it work? • Small tidal volumes at high frequency are generated by low amplitude pressure oscillations. These tidal volumes that are approximately equal to dead space. • High mean airway pressures (PEEP) provides distending pressure. • HFOV can provide 5-15 Hz equal to (900 breaths/min. • What is HFOV • HFOV has all of the elements of high frequency ventilation discussed previously. • Also provides a bias oscillatory gas flow used to generates positive and negative pressure fluctuations referred to as amplitudes or (Delta-P) Oscillation/Frequency Hz Amplitude MAP/PEEP
HFOV: 3100A • External Air/O2 Blender • 1. Provides blended air/O2 and cooling to the oscillator • Oscillator Subsystem • Uses an • 1.electronic control circuit called the square wave form driver • 2. Forward and backward linear motion provides inspiratory and expiratory gas flow. • 3. Provides frequent small VT in HZ • External Humidifier • 1. Attaches and functions with the patient’s circuit • 2. Capable of flows up to 40 LPM • Pneumatic Logic and Control System • Comprised of 4 pneumonic controls • 1. Bias flow • 2. Mean Pressure adjustments • 3. Mean pressure limit control • 4. Patient circuit calibration adjustment • Pressure Monitoring System • 1. Safety and alarms rely on this system • 2. The PMS senses pressures within the patient’s circuit through the tubing that runs from the y-coupler • Electronic Power Supply • Monitors: • 1. Alarms • 2. Pressures • 3. Function of the oscillator • Patient Circuit • Provides: • 1. Bias flow/pressure • 2. Pressurized oscillations • 3. Pressure limiting
3100 A 18 • 3100A Interface: • Bias flow knob • Mean Pressure adjustment • Mean Pressure Limit • Power • % Inspiratory Time • Frequency • Start/Stop • Mean Airway Pressure • Set Max Paw • Set Min Paw • Paw >50 cm H2O • Paw <20 cm H2O • Power failure Button • Reset • 15a Battery Low • 15b Source Gas Low • 16. Oscillator Overheated • 17. Oscillator stopped • 18. 45 second Silence 4 13-14 8 3 11 5 9 7 2 6 10 12 1 15b 16 17 15a
Adjustable Parameters • Amplitude: • Determines the volume of gas generated by each frequency wave • Oscillation/ Frequency (Hz) • Frequency = The Rate • 15 Hz =900 BPM for neonates • 12-14 Hz =600 BPM for termed infants • 8 Hz =480 BPM for children 6-10 kg • 6 Hz =360 BPM for children above 10 kg • IT% • Inspiratory Time Percentage • 33% IT = 22 milliseconds a 15 Hz • I:E: For HFOV • I:E also determines the time for movement of the piston to generate another oscillatory breath. • Initial I:E of 1:2 for 3-15 Hz at 33% IT • MAP/PEEP: • Maintains constant distending pressure in the airway • 15-18 cmH2O • Amplitudes • 2.5 for • 3.0 for • 4.0 for • 5.0 for • 6.0 for • 7.0 for Weight: kg/mg <2.0 kg. <3.0 kg <2.5-4.0 kg 4.0-5.0 kg < 10 kg >20 kg
Pulmonary Diseases and Disorders treated with HFOV https://www.youtube.com/watch?v=dHuXtoODHuA
Pneumopercardium Pneumopertioneum Sub cu-emphysema ARDS Pneumothorax Pneumomediastinum
Potential Advantages of HFOV are 1. Uniform inflation of the lung fields2. Improves gas exchange 3. Improves lung mechanics 4. Enables stable lung inflationo Allows recruitment of alveolar spaceo Reduces the risk of volutrauma o Reduces risk of high peak airway pressure (PIP)o Reduces the risk of airway stretchingo Improves V/Q matching5. Reduces air leak 6. Decreases the amount of inflammatory mediators and alveolar edema7. Prevents the development of hyaline membrane disease (HMD)
HFOV CMV CMV VS HFOV During CMV, there are swings between the zones of injury from inspiration to expiration. During HFOV, the entire cycle operates in the “safe window” and avoids the injury zones. INJURY INJURY
Zone of Overdistention Volume Safe window Zone of Derecruitment and atelectasis Pressure HFOV is used to prevent Ventilator Induced Lung Injury Goal is to avoid injury zones and operate in the safe window
Indications: When traditional ventilation fails Airleak syndromes For patients with severely low lung compliance Refractory hypoxemia • Contraindications: • ICP • obstructive lung disease • increased airway resistance (small endotracheal tube) • asthma • secretions • increased physiological dead space
Work Citations Page: Alves, Amanda. “High Frequency Oscillatory Ventilation HFOV; a new strategy in the Treatment of patients with Acute Respiratory Distress Syndrome and low lung compliance.” CIMC 2000. Web 13 August 2014. Birch, Pita. “Newborn Services Clinical Guideline High Frequency Oscillatory Ventilation.” Web. 14 August 2014. http://www.adhb.govt.nz/newborn/guidelines/respiratory/hfov/hfov.htm CareFusion; “3100A High frequency oscillatory ventilation; Operator’s manual.” CareFusion Corporation. 222745 Savi Ranch Parkway Yorba Linda, CA 92887-4668. Web 18 August 2014 Haines, Mike. “Mechanical Ventilation: High Frequency Ventilation.” Respiratory Therapy Files. http://www.respiratorytherapyfiles.net Web. 8 August 2014. Jeng, Mei-Jy. Lee, Chen, Soong. “Neonatal air leak syndrome and the role of high-frequency ventilation.” Sci Verse Science Direct Journal of the Chinese Medical Association 75 (2012) 551e559 Web. 8 August 2014. http://homepage.vghtpe.gov.tw/~jcma/75/11/551.pdf Prost, Allen. “High Frequency Oscillation Ventillation.avi.” Youtube.com. 2011. Web 24 Aug. 2014. Slee-Wijffels1, Fieke YAM. RM van der Vaart, Twisk, Markhorst, Plötz5 “High-frequency oscillatory ventilation in children: a single-center experience of 53 cases, pp. R274” Open Access. 16 Web August 2104. http://www.biomedcentral.com/content/pdf/cc3520.pdf Slee-Wijffels1, Fieke YAM. RM van der Vaart, Twisk, Markhorst, Plötz5 “High-frequency oscillatory ventilation in children: a single-center experience of 53 cases, pp. R274” Open Access. 16 Web August 2104. http://www.biomedcentral.com/content/pdf/cc3520.pdf