1 / 14

Martina Rastovac Mentor: A. Žmegač Horvat

Pancreatic Carcinoma. Martina Rastovac Mentor: A. Žmegač Horvat. Actor Patrick Swayze died after a 20-month battle with pancreatic cancer . He was 57. Epidemiology: < 2% of all malignancies ~ 6500 deaths/year Typical patient: male > 60yrs old Risk factors: smoking alcohol

saged
Download Presentation

Martina Rastovac Mentor: A. Žmegač Horvat

An Image/Link below is provided (as is) to download presentation Download Policy: Content on the Website is provided to you AS IS for your information and personal use and may not be sold / licensed / shared on other websites without getting consent from its author. Content is provided to you AS IS for your information and personal use only. Download presentation by click this link. While downloading, if for some reason you are not able to download a presentation, the publisher may have deleted the file from their server. During download, if you can't get a presentation, the file might be deleted by the publisher.

E N D

Presentation Transcript

  1. Pancreatic Carcinoma Martina Rastovac Mentor: A. Žmegač Horvat

  2. Actor Patrick Swayze died after a 20-month battle with pancreatic cancer. He was 57.

  3. Epidemiology: • < 2% of all malignancies • ~ 6500 deaths/year • Typical patient: • male > 60yrs old • Risk factors: • smoking • alcohol • carcinogens • chronic pancreatitis

  4. Pancreas: head body tail

  5. Symptoms & signs: • jaundice • pain in the upper or middle abdomen and back • unexplaind weight loss • loss of appetite • fatigue

  6. Investigations: • transabdominal ultrasound • contrast-enhanced spiral CT scan • laparoscopy • ERCP • percutaneous needle biopsy • MRI scanning and endoscopic ultrasound • several tumour markers (CA19-9)

  7. Pathology: • mostly ductal adenocarcinoma (metastasizes early; presents late) Location of tumor: - 60% head - 25% body - 15% tail

  8. Stages of pancreatic cancer: I II III IV

  9. Treatment: • surgery • Whipple`s procedure • total pancreatectomy • distal pancreatectomy • radiation therapy • chemotherapy

  10. Whipple`s procedure:

  11. WHO Pain relief ladder Freedom from cancer pain

  12. Prognosis: • dismal Mean survival: < 6 months 5yr survival: < 2 % After Whipple`s procedure: 5-14% Better if:tumour < 3 cm no nodes involved negative resection margins at surgery ampullary or islet cell tumors

  13. References: • http://www.meb.uni-bonn.de/cancer.gov/CDR0000062957.html • Longmore, Oxford Handbook of Clinical Medicine, Oxford University Press, 2010

More Related