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P R K in 2005. Bernard Mathys, MD Brussels. Brief history. 15 Y of follow-up Excimer laser Relatively easy technique Short learning curve. Limits. Pain Regression Haze ( > -6D). PRK fights back. Complications of Lasik Epithelial ingrowth Striae, folds SOS Ectasia
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P R Kin 2005 Bernard Mathys, MD Brussels www.drmathys.be BSCRS 2005
Brief history • 15 Y of follow-up • Excimer laser • Relatively easy technique • Short learning curve www.drmathys.be BSCRS 2005
Limits • Pain • Regression • Haze ( > -6D) www.drmathys.be BSCRS 2005
PRK fights back • Complications of Lasik • Epithelial ingrowth • Striae, folds • SOS • Ectasia • Flap induced HOA • Problem flap size/wide OZ for hyperopia www.drmathys.be BSCRS 2005
PRK improved • Improved lasers: scanning, flying spot, Gaussian • Improved OZ, transition Z, blend Z • Improved nomogram • Improved tracker: centration, cyclotorsion, frequency, mechanical response ? • Aspheric profile: better for HOA ? www.drmathys.be BSCRS 2005
Advantages • Limits induced HOA • Lower rate of irregular astigmatism • Wave-front guided: Fourier > Zernicke ? • Customized treatment www.drmathys.be BSCRS 2005
Results www.drmathys.be BSCRS 2005
No higher RMS postop for high correction • No higher RMS postop for large OZ • Seems to reduce RMS for OZ 6 – 6.5 • Safe and effective: no loss of VA www.drmathys.be BSCRS 2005
RMS changes www.drmathys.be BSCRS 2005
And so…PRK, Lasek > Lasik ? • Flap induced HOA: nomogram correction • FDA studies for Lasik. PRK ? • In fact, photoablation creates HOA !! • No « real » studies in litterature www.drmathys.be BSCRS 2005
PRK Follow-up • Pain • Fluctuations • Haze www.drmathys.be BSCRS 2005
PRK best treatment • Corneal cooling • Quick removal of the epithelium • CL • AINS (ketorolac) 3d • Tears • Steroïds ? www.drmathys.be BSCRS 2005
AINS (ketorolac) www.drmathys.be BSCRS 2005
PRK haze ? • Activated keratocytes – collagen I-III • More frequent if: • delayed epithelial response • deep ablation, > -9D • broad beam, more energy, retreatment Gabbato,Ophtal. online, dec 2004 • Max 3 to 6 M • Decreases with time: metalloprotease Kato • After 1 Y: scar • MMC 0.02% 2 min www.drmathys.be BSCRS 2005
Best healing response ? • Amniotic membrane ? • Interferon ? • Growth factor ? • PA ? www.drmathys.be BSCRS 2005
So…PRK indications ? • Up to -5 D • K < 39 and > 48 • KT subclinical • Thin cornea • Dry eyes • High astigmatism • Army, pilots, athlete www.drmathys.be BSCRS 2005
Even more indications… • Hyperopes • Refraction error after IOL • Refraction error after RK • Refraction error after corneal graft www.drmathys.be BSCRS 2005
PRK after RK www.drmathys.be BSCRS 2005
And PTK ? • Irregular astigmatism • Recurrent erosion • Reshaping • Herpes (under treatment) www.drmathys.be BSCRS 2005
Then: • Do not be ashamed to perform PRK • Many indications • Haze problems tend to diminish • Lasek = disguised PRK • Not a single ectasia after PRK • Good PRK much better than a bad Lasik !! www.drmathys.be BSCRS 2005
Good PRK >< Bad Lasik www.drmathys.be BSCRS 2005
Thin corneas www.drmathys.be BSCRS 2005
Follow-up 1 Y www.drmathys.be BSCRS 2005
Limited induced aberrations www.drmathys.be BSCRS 2005
High astigmatism www.drmathys.be BSCRS 2005
Same patient, topography www.drmathys.be BSCRS 2005
Thank you for your attention www.drmathys.be BSCRS 2005