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Test results Hgb 77 g/L MCV 66 f/L RBC 3.2 x10 12 /L WBC 5.6 x10 6 /L Plat 525 x10 9 /L. Blood film. This is a 55 year old woman who has fatigue. Her only other symptom is a craving for chewing ice cubes. Apart from being pale her examination is normal.
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Test results Hgb 77 g/L MCV 66f/L RBC 3.2 x1012/L WBC 5.6 x106/L Plat 525 x109/L Blood film This is a 55 year old woman who has fatigue. Her only other symptom is a craving for chewing ice cubes. Apart from being pale her examination is normal.
Which one of the following tests would best define the type of anemia she has ? A. Hgb electropheresis B. Serum iron and iron-binding capacity C. Serum ferritin D. Serum transferrin E. Bone marrow iron
Test results Hgb 135 g/L MCV 65 fL RBC 5.4 x1012/L WBC 6.5 x106/L Plat 355 x109/L Blood film A 44 year old executive is sent to you for an insurance examination. He is fit, but on examination he has mild hypertension.
Test results Hgb 135 g/L MCV 65 fL RBC 5.4 x1012/L WBC 6.5 x106/L Plat 355 x109/L Blood film microcytosis hypochromia target teardrop basophilic stippling A 44 year old executive is sent to you for an insurance examination. He is fit, but on examination he has mild hypertension.
Which test is likely to give a diagnosis in this case ? A. Serum ferritin B. Serum transferrin C. Sickle Cell screen D. Hgb electropheresis E. Liver function tests
Test results Hgb 99 g/L MCV 100 fL RBC 3.7 x1012/L WBC 3.4 x106/L Plat 117 x109/L Retic count: elevated bili 35 mol/L This is an 18 year old boy who you are investigating for Jaundice. He has this intermittently for some time. His family are Christian Scientists. Physical exam shows jaundice and splenomegaly
Which of the following would be most helpful in identifying this young man’s problem ? A. Reticulocyte count B. Osmotic fragility test C. DAT (Coomb’s test) D. Bone marrow test E. Family studies
Test results Hgb 99 g/L MCV 100 fL RBC 3.7 x1012/L WBC 3.4 x106/L Plat 117 x109/L bili 35 mol/L blood film polychromasia spherocytes This is an 18 year old boy who you are investigating for Jaundice. He has this intermittently for some time. His family are Christian Scientists. Physical exam shows jaundice and splenomegaly
Test results Hgb 142 g/L MCV 105 fL RBC 4.9 x1012/L WBC 6.7 x106/L Plat 105 x109/L Blood Film A 46 year old diplomat is referred to you because of abnormal blood results. On review of these you suspect the cause and order appropriate blood tests.
Test results Hgb 142 g/L MCV 105 fL RBC 4.9 x1012/L WBC 6.7 x106/L Plat 105 x109/L Blood Film Macrocytosis Target cells stomatocytes A 46 year old diplomat is referred to you because of abnormal blood results. On review of these you suspect the cause and order appropriate blood tests.
What tests would you order on receiving these results ? A. Serum B12 and folate B. Bone marrow aspirate C. Serum lipid studies D. Liver function tests E. Thyroid function tests
Test results Hgb 85 g/L MCV 110 fL RBC 3.9 x1012/L WBC 2.4 x106/L Plat 89 x109/L Retic count low A 65 year old woman is referred to you because of memory loss. Her family physician had received tests which included bilirubin of 28 mol/L and an LDH of 1560 U/L. He was puzzled by these results.
Test results Hgb 85 g/L MCV 110 fL RBC 3.9 x1012/L WBC 2.4 x106/L Plat 89 x109/L Blood Film Macrocytosis oval macroytes hypersegmented neutrophils A 65 year old woman is referred to you because of memory loss. Her family physician had received tests which included bilirubin of 28 mol/L and an LDH of 1560 U/L. He was puzzled by these results.
Which one of the following tests is most appropriate ? A. Liver function B. Thyroid function C. RBC folate D. Serum B12 E. Bone marrow aspirate
Test results Hgb 103 g/L MCV 99 fL RBC 3.8 x1012/L WBC 3.4 x106/L Plat 125 x109/L Retic ‘normal’ A 65 year old woman complains of back pain. Her X-rays show diffuse osteoporosis. She also complains of increased thirst and drowsiness.
Test results Hgb 103 g/L MCV 99 fL RBC 3.8 x1012/L WBC 3.4 x106/L Plat 125 x109/L Blood Film rouleaux background staining A 65 year old woman complains of back pain. Her X-rays show diffuse osteoporosis. She also complains of increased thirst and drowsiness.
Which one of these tests would most likely lead to the diagnosis ? A. Serum osmolarity B. Serum viscosity C. Serum protein electrophersis D. Serum TSH E. Serum PTH
Test results Hgb 115 g/L MCV 115 fL RBC 2.2 x1012/L WBC 8.4 x106/L Plat 246 x109/L Retic count: elevated You admit a 36 year old woman with pneumonia. She has fever, shortness of breath and requires oxygen. She is also noted to be anemic.
Test results Hgb 115 g/L MCV 115 fL RBC 2.2 x1012/L WBC 8.4 x106/L Plat 246 x109/L Blood Film RBC agglutination You admit a 36 year old woman with pneumonia. She has fever, shortness of breath and requires oxygen. She is also noted to be anemic.
These test results would help you choose which one of these antibiotics ? A. Cephalexin B. Penicillin G C. Azithromycin D. Sulfamethoxazole E. Ciprofloxacin
Test results Hgb 75 g/L MCV 107fL RBC 2.8 x1012/L WBC 8.9 x106/L Plat 377 x109/L Blood Film An 18 year old woman has symptoms of cystitis. After urine cultures are taken she is given Sulfamethoxazole. Her urinary symptoms improve but she becomes short of breath. A week later on follow-up her investigation shows.
Test results Hgb 75 g/L MCV 107fL RBC 2.8 x1012/L WBC 8.9 x106/L Plat 377 x109/L Blood Film polyychromasia blister bite cells An 18 year old woman has symptoms of cystitis. After urine cultures are taken she is given Sulfamethoxazole. Her urinary symptoms improve but she becomes short of breath. A week later on follow-up her investigation shows.
What type of anemia is causing this problem ? A. An idiosyncratic drug reaction B. An allergic drug reaction C. Marrow suppressive effect D. Immune hemolysis E. Oxidative hemolysis
Test results Hgb 115 g/L MCV 91 fL RBC 4.1 x1012/L WBC 14.5 x106/L Plat 52 x109/L You are called to see this 29 year old primip in the case room. The obstetrician is concerned about her platelet count. She is well but a bit hypertensive.
Test results Hgb 115 g/L MCV 91 fL RBC 4.1 x1012/L WBC 14.5 x106/L Plat 52 x109/L Blood Film polychromasia rbc fragments thrombocytopenia You are called to see this 29 year old primip in the case room. The obstetrician is concerned about her platelet count. She is well but a bit hypertensive.
What diagnosis is most likely ? A. ITP ( immune thrombocytopenia ) B. TTP ( thrombotic thrombocytopenic purpura) C. PIH (pre-eclampsia) D. Benign thrombocytopenia of pregnancy E. DIC (disseminated intravascular coagopathy)
Test results Hgb 115 g/L MCV 105 fL RBC 3.8 x1012/L WBC 9.2 x106/L Plat 420 x109/L Blood Film This 35 year old man is sent to you because of unusual blood results. His complaints are of fatigue and an episodic itchy rash.
Test results Hgb 99 g/L MCV 96 fl RBC 3.4 x1012/L WBC 3.65 x106/L Plat 560 x109/L Retic: low You are asked to asses a 72 year old woman for anemia and splenomegaly. She has been losing weight for 1 year. She has had 2 episodes of gout.
Test results Hgb 99 g/L MCV 96 fl RBC 3.4 x1012/L WBC 3.65 x106/L Plat 560 x109/L Blood Film thromboytosis tear drop cells leukoerythroblstic You are asked to asses a 72 year old woman for anemia and splenomegaly. She has been losing weight for 1 year. She has had 2 episodes of gout.
What test would give a definitive diagnosis ? A. LAP score B. Osmotic fragility C. Hgb electropheresis D. Bone scan E. Bone marrow biopsy
…splenomegaly • Hematologic conditions • Myelofibrosis • Some hemolytic anemias • Myeloproliferative conditions • leukemia • Lymphomas • Non-hematologic • Congestive (cirrhosis) • Infiltrative: malignant, non-malignant • Infectious (mono) • Inflammatory:
Lymphadenopathy • Abnormal in size, consistency, number • Generalized • Localized
Test results Hgb 136 g/L MCV 88 fL RBC 4.9 x1012/L WBC 17.3 x106/L Plat 110 x109/L Blood Film This 24 year old man has acute abdominal pain. He has not been feeling well for 5 days. After a baseball game he had acute upper abdominal pain and was quite tender in the upper abdomen. The surgeon asks you to see the patient.
Test results Hgb 136 g/L MCV 88 fL RBC 4.9 x1012/L WBC 17.3 x106/L Plat 110 x109/L Blood Film variant lymphocytes atypical reactive This 24 year old man has acute abdominal pain. He has not been feeling well for 5 days. After a baseball game he had acute upper abdominal pain and was quite tender in the upper abdomen. The surgeon asks you to see the patient.
What is the disorder most likely responsible for his condition ? A. Acute leukemia B. Pancreatitis C. Malaria D. Infectious mononucleosis E. Liver abcess